ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2026
Re-intervention in endoscopic ultrasound-guided walled-off necrosis drainage with metal stents: Identifying high-risk morphologies.
Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveEndoscopic ultrasound (EUS)-guided drainage with metal stents is a standard therapy for walled-off necrosis (WON). However, some patients require re-interventions such as stent unclogging, necrosectomy or percutaneous drainage. This study aimed at identifying predictors of re-intervention to facilitate risk stratification and optimize management.
methodsThis study included consecutive patients who underwent EUS-guided WON drainage with metal stents between January 2023 and December 2024 at a tertiary referral center. Demographic, clinical and radiological data was collected prospectively. Multi-variate logistic regression identified independent predictors of re-intervention. Model performance was evaluated using receiver operating characteristic (ROC) curve, calibration plot and decision curve analysis. Model's diagnostic performance was evaluated in the validation cohort.
resultsOf 500 patients (83.2% male), 28.6% had alcohol-related and 10% had biliary pancreatitis. Re-intervention was required in 24% (n = 120), primarily for stent unclogging (85.8%), nasocystic tube placement (70%) and necrosectomy (50%). Independent predictors of re-intervention included WON size (odds ratio [OR] 1.38; 95% confidence interval [CI], 1.25-1.52), paracolic extension (OR 9.96; 95% CI, 1.77-55.98) and solid debris content (OR 1.10; 95% CI, 1.08-1.13). The model demonstrated good discrimination (area under the curve [AUC] = 0.85) and calibration (Hosmer-Lemeshow p = 0.19). The overall accuracy of the model in the validation cohort was 86.67% (95% CI, 73.21-94.95%). Adverse events occurred in 6% of patients, including bleeding (n = 11), stent migration (n = 13) and sepsis-related death (n = 6).
conclusionLarger WON size, paracolic extension and higher solid debris content are independent predictors of re-intervention after EUS-guided drainage. Early identification of these factors may allow for individualized step-up therapy and improved clinical outcomes.
Indexed as
Identifiers
41748976What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.