Evidence map›Paper›PMID 41748952›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Patterns of injury, management stratification, and inpatient outcomes in pediatric complete cervical spinal cord injury: insights from a national database.

Sean Inzerillo, Mert Karabacak, Rosivel Galvez, Paul Mastrokostas, Matthew T Carr, Peter Morgenstern, Konstantinos Margetis

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Sean InzerilloCollege of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Mert KarabacakDepartment of Neurosurgery, Mount Sinai Health System, New York, NY, USA.
Rosivel GalvezCollege of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Paul MastrokostasCollege of Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.
Matthew T CarrDepartment of Neurosurgery, Mount Sinai Health System, New York, NY, USA.
Peter MorgensternDepartment of Neurosurgery, Mount Sinai Health System, New York, NY, USA.
Konstantinos MargetisDepartment of Neurosurgery, Mount Sinai Health System, New York, NY, USA. Konstantinos.Margetis@mountsinai.org.

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No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePediatric complete cervical spinal cord injury (cSCI) is rare and associated with severe morbidity and mortality, yet limited data exist to guide management. This study aimed to describe national injury characteristics, management stratification, and inpatient outcomes among children with complete cSCI.

methodsPediatric patients (< 18 years) with complete cSCI were identified from the American College of Surgeons Trauma Quality Program database (2019-2021). Cases with severe head trauma or pre-hospital deaths were excluded. Patients were grouped into surgical and non-surgical cohorts. Univariate analyses compared demographic, clinical, injury-related, and hospital outcome variables. Analyses were performed in Python 3.7 using Google Colab, with significance set at p < 0.05.

resultsAmong 125 pediatric patients with complete cSCI (78.4% male, mean age 14.3 years), surgical management (75.2%) was associated with falls (27.7% vs. 3.2%, p = 0.003) and combined fracture-dislocations (44.7% vs. 16.1%, p = 0.008), while non-surgical cases were linked to assaults (41.9% vs. 10.6%, p < 0.001) and injuries at C3 or higher levels (29.0% vs. 10.6%, p = 0.029). Intensive care was universally required, with 73.6% needing ventilation. Most patients (88.8%) were discharged to institutional care, with a total mortality rate of 4.8%. Mortality was significantly lower in the surgical group (1.1% vs. 16.1%, p = 0.004).

conclusionThis analysis identified differing injury patterns, with surgery linked to falls and fracture-dislocations and non-surgical care to upper cervical injuries. Observed differences in mortality should be interpreted cautiously given selection bias and data constraints. Prospective studies are needed.

Indexed as

Cervical CordSpinal Cord InjuriesAdolescentCervical VertebraeChildChild, PreschoolDatabases, FactualFemaleHumansMaleTreatment OutcomeComplete cervical spinal cord injuryInpatient outcomesNational databasePediatricsSurgical managementTrauma quality program

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.