ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026
Neuropsychiatric manifestations of Wilson's disease.
Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical, cognitive and neuropsychiatric correlates of personality in Wilson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundWilson’s disease is a rare autosomal recessive disorder of copper metabolism, characterized by copper accumulation in many tissues, especially in the liver and the brain. PATHOPHYSIOLOGY: In the brain, pathological changes mainly involve the basal ganglia, explaining the high prevalence of movement disorders and psychiatric symptoms in Wilson’s disease patients. DIAGNOSIS: Neuropsychiatric symptoms usually appear at around 20 years of age, but the age of presentation range is very broad. Brain magnetic resonance imaging may detect intensity signal abnormalities in the basal ganglia, thalamus and/or brainstem in Wilson’s disease patients with or without neuropsychiatric symptoms. TREATMENT: Neuro-Wilson’s disease treatment includes medications leading to negative copper body balance, as well as drugs for symptomatic treatment of neuropsychiatric symptoms.
conclusionWilson’s disease includes a wide spectrum of phenotypic presentations, thus making diagnosis difficult. Since neuropsychiatric symptoms may represent the first clinical manifestation of Wilson’s disease, early diagnosis is essential to start prompt treatment.
Indexed as
Identifiers
41748943What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.