Evidence map›Paper›PMID 41748910›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

The association between cannabis use and brain reward anticipation: a 12-month longitudinal study of adults and adolescents who use cannabis and age-matched controls.

Martine Skumlien, Simiao Wang, Tom P Freeman, Molly Eddison, Kat Petrilli, Matthew B Wall, Claire Mokrysz, H Valerie Curran, Will Lawn

Abstract read
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In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martine SkumlienDepartment of Addictions, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. martine.skumlien@kcl.ac.uk.ORCID http://orcid.org/0000-0003-3552-2653
Simiao WangDepartment of Addictions, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Tom P FreemanAddiction and Mental Health Group (AIM), Department of Psychology, University of Bath, Bath, UK.ORCID http://orcid.org/0000-0002-5667-507X
Molly EddisonDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0009-0005-0553-6167
Kat PetrilliDepartment of Addictions, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Matthew B WallPerceptive, London, UK.
Claire MokryszClinical Psychopharmacology Unit, Clinical, Educational and Health Psychology Department, University College London, London, UK.
H Valerie CurranClinical Psychopharmacology Unit, Clinical, Educational and Health Psychology Department, University College London, London, UK.ORCID http://orcid.org/0000-0001-6011-6978
Will LawnDepartment of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-0143-2724

Funding

RCUK | Medical Research Council (MRC) MR/P012728/1
6 · The paper itself

Abstract

Substance use has been associated with blunted brain responses to non-drug rewards, but findings in people who use cannabis are mixed. Adolescents may be uniquely vulnerable to cannabis-related disruption to reward processing due to ongoing neuromaturation, but longitudinal research is lacking. In this longitudinal fMRI study, we compared brain measures of reward anticipation in 46 adolescents (16-17 years) and adults (26-29 years) who used cannabis (1-7 days/week) and 50 age-matched controls with the Monetary Incentive Delay task at baseline and 12-month follow-up. Region of interest (ROI) analyses adjusted for cigarette/roll-up use, depression, and risk-taking found that reward anticipation activity decreased in the right (p = 0.05, η

Indexed as

Anticipation, PsychologicalBrainMarijuana AbuseMarijuana UseRewardAdolescentAdultFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleYoung Adult

Identifiers

PMID41748910
PMCPMC13389008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.