Articlenpj antimicrobials and resistance2026
Five-decade global expansion of Staphylococcus argenteus ST2250 shapes antimicrobial resistance dynamics.
Article in npj antimicrobials and resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Staphylococcus argenteus is implicated in various superficial and invasive diseases in humans, and multidrug resistance has been increasingly reported. Here, we aim to elucidate the bacterial features shaping the global spread of antimicrobial resistant S. argenteus. The global population contained a heterogeneous collection of antimicrobial resistance (AMR) genes, virulence genes and plasmid replicon types. Of the 13 sequence types (ST) present, ST2250 made up 56.2% of the dataset. We estimate its most recent common ancestor to have emerged in 1967. Two sublineages of ST2250 with distinct AMR gene content appeared separately in Asia and Europe in 1989 and 1992, respectively. The effective population size of ST2250 has soared in the past five decades, although there is indication of a recent decline. Overall, our results show that the AMR pool of S. argenteus is driven in part by the clonal expansion and subsequent diversification of ST2250 worldwide.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.