Evidence map›Paper›PMID 41748711›Full record

ArticleScientific reports2026

Reevaluation of ECGs of a German non coronary sudden cardiac arrest cohort.

Fabienne Kreimer, Pia Thiesing, Ibrahim Akin, Nazha Hamdani, Michael Gotzmann, Andreas Mügge, Assem Aweimer, Ibrahim El-Battrawy

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Fabienne Kreimer *Department of Cardiology II - Rhythmology, University Hospital Münster, Münster, Germany.
Pia Thiesing *Cardiology and Rhythmology, University Hospital St Josef Hospital, Ruhr University, Bochum, Germany.
Ibrahim AkinFirst Department of Medicine, University Medical Center Mannheim, Mannheim, Germany.
Nazha HamdaniCardiology and Rhythmology, University Hospital St Josef Hospital, Ruhr University, Bochum, Germany.
Michael GotzmannCardiology and Rhythmology, University Hospital St Josef Hospital, Ruhr University, Bochum, Germany.
Andreas MüggeCardiology and Rhythmology, University Hospital St Josef Hospital, Ruhr University, Bochum, Germany.
Assem AweimerDepartment of Cardiology, University Hospital Bergmannsheil, Ruhr University, Bochum, Germany.
Ibrahim El-BattrawyCardiology and Rhythmology, University Hospital St Josef Hospital, Ruhr University, Bochum, Germany. ibrahim.elbattrawy2006@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While primarily a disease of older adults due to coronary artery disease, sudden cardiac arrest (SCA) also affects younger individuals, particularly those with genetic predispositions or congenital heart defects. This study aimed to systematically investigate SCA in younger patients (aged ≤ 65 years), focusing on non-coronary artery-related causes. Patients admitted due to SCA or acute resuscitation scenarios at the University Hospital Bergmannsheil in Bochum, Germany, between 2010 and 2021, were comprehensively investigated. Patients were categorized into groups based on their diagnosed etiology, with non-coronary causes being the primary focus of this analysis. 232 patients with SCA were included. The median age was 52 years, 66.7% were male. The causes were idiopathic (54.2%), cardiomyopathies (29.2%), myocarditis (8.3%), valve diseases (2.1%) and channelopathies (6.3%). Two independent cardiologists reviewed all ECGs, at least two from each case. Post-resuscitation ECG analysis identified Short- and Long-QT-syndrome in two patients previously classified as idiopathic SCA. SCA was witnessed by bystanders in 87.5% of cases, with layperson cardiopulmonary resuscitation in 45.8%. SCA occurred predominantly at home (37.5%) and in public places (29.2%). In-hospital mortality was 29.2%. During a mean follow-up of 53.2 ± 7.3 months, three patients died. ICDs documented ventricular tachyarrhythmias in nine patients. This study comprehensively analyzed 48 non-coronary SCA patients from a cohort of 232 SCA cases. A case of short QT syndrome and a case of long-QT syndrome was identified in an SCA cohort, emphasizing the importance of repeated ECG analysis after cardiac arrest.

Indexed as

Death, Sudden, CardiacElectrocardiographyAdultArrhythmias, CardiacCardiopulmonary ResuscitationFemaleGermanyHumansMaleMiddle AgedCardiopulmonary resuscitationLong-QT-syndromeShort-QT-syndromeSudden cardiac arrestSudden cardiac deathVentricular fibrillation

Identifiers

PMID41748711
PMCPMC12949055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.