Evidence map›Paper›PMID 41748704›Full record

ArticleScientific reports2026

A transparent AI assurance and benchmarking framework for EEG seizure detection on TUSZ seeded with a reproducible gradient-boosting ensemble.

Morteza Zabihi, Emily J Gilmore, Kan Ding, Eric S Rosenthal

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Morteza ZabihiDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. mzabihi@mgh.harvard.edu.
Emily J GilmoreDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Kan DingUniversity of Texas Southwestern, Dallas, TX, USA.
Eric S RosenthalDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Funding

NIH/NINDS R01NS117904 (ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenation)
6 · The paper itself

Abstract

Reliable evaluation is essential for clinically usable automated electroencephalography (EEG) seizure detection. Although the TUH EEG Seizure Corpus (TUSZ) is the de facto benchmark, studies often use non-canonical splits, mix patients across partitions, or evaluate on seizure-only segments, making results hard to compare. We release an open-source, transparent benchmark for offline binary seizure detection on TUSZ v2.0.3 that strictly follows the official Train/Dev/Eval partition and evaluates in continuous EEG. Each 60-s window (15-s stride) is mapped to expert features and classified by three CatBoost ensembles: a within-window base model and two temporal-context models (full and high-sensitivity). We cast operating-point selection as an alarm-budget decision problem: on the Development set, we jointly choose the score threshold and event post-processing to maximize event sensitivity while enforcing specificity ≥ 0.93 and false alarms ≤ 0.69 per hour, then freeze this decision policy and apply it once to the held-out Eval set. On Eval, we obtain AUROC 0.92 and balanced accuracy 0.83 at the window level and event sensitivity 0.75 at 0.68 false alarms/hour (time-based positive predictive value [PPV] 0.57; recall 0.76). We provide the protocol and results as a reproducible baseline and clinically oriented benchmark for comparing past and future models.

Indexed as

Artificial IntelligenceElectroencephalographySeizuresAlgorithmsBenchmarkingBoosting Machine Learning AlgorithmsHumansSensitivity and SpecificityElectroencephalogramGradient boostingSeizure detectionTemporal contextTUH EEG Seizure Corpus (TUSZ)

Identifiers

PMID41748704
PMCPMC13049040

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.