ArticleCancer control : journal of the Moffitt Cancer Center
A Cross-Sectional Study Assessing Association of Renal Cell Carcinoma Pathological Grade and Stage With Body Mass Index and Obesity Related Factors.
Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Variation in image-assessed abdominal adiposity and skeletal muscle and their associations with pathological characteristics in renal cell carcinoma.Cancer causes & control : CCC · 2026Article
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10 authors.
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Abstract
PurposeThis cross-sectional study explored associations of BMI with renal cell carcinoma (RCC) pathological grade and stage, and how these associations vary by BMI-related factors, to better understand the obesity paradox.MethodData was obtained from 2 academic institutions for this cross-sectional study of RCC patients who underwent surgical treatment. Logistic regression models were used to identify BMI-related factors and to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for diagnosis with high grade or advanced stage.ResultsA total of 1949 cases, 1526 from Roswell Park Comprehensive Cancer Center (Roswell Park) and 423 from University of Arizona Baner-University Medical Center Tucson (BUMCT), were included. In both datasets, obesity was significantly associated with lower odds of high grade compared with non-obese (OR 0.69, 95% CI 0.54-0.88 in Roswell Park, OR 0.62, 95% CI 0.41-0.94 in BUMCT). In Roswell Park, unintentional weight loss at the time of surgery was associated with higher odds of high grade (OR 3.81, 95% CI 2.38-6.09) and advanced stage (OR 4.12, 95% CI 2.74-6.20). In both datasets, older age was associated with reduced odds of obesity and higher odds of high grade, and heterogeneous associations between obesity and high grade by age group were observed (P
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