Evidence map›Paper›PMID 41746594›Full record

ArticleOphthalmology and therapy2026

Synergising Macular Function and Structure in Diabetic Macular Oedema to Improve Patient Care: An International Delphi Consensus.

Christiana Dinah, Andrew Chang, Pierre-Henry Gabrielle, Rishi Singh, Javier Zarranz-Ventura, Insaf Saffar, Marloes Bagijn, Aude Ambresin

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christiana DinahLondon Northwest University Healthcare NHS Trust, London, UK. christiana.dinah@nhs.net.ORCID http://orcid.org/0000-0002-0815-4771
Andrew ChangSydney Eye Hospital, Sydney, NSW, 2000, Australia.
Pierre-Henry GabrielleDijon University Hospital, 21000, Dijon, France.
Rishi SinghCentre for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, Cleveland, USA.
Javier Zarranz-VenturaHospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.
Insaf SaffarF. Hoffmann-La Roche Limited, Basel, Switzerland.
Marloes BagijnF. Hoffmann-La Roche Limited, Basel, Switzerland.
Aude AmbresinSwiss Visio Retina Research Centre at Swiss Visio Montchoisi, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe correlation between diabetic macular oedema (DMO) structural and functional assessments and their reflection of patient impact lacks consensus. This study aims to understand the ophthalmology community's thoughts on optimising patient care by improving functional and structural assessments.

methodsThe process employed a modified Delphi methodology. Following a literature review, a steering committee of six experts developed 40 statements under three consensus topics. The statements were globally distributed via an online, four-point Likert scale survey using a snowball sampling technique.

resultsSurvey responses (n = 93) were collated anonymously and independently analysed. Consensus was achieved in 35 statements (88%). There was strong agreement that routinely used assessments for DMO may not accurately reflect the level of vision impairment experienced by the patient and that there is a need for a composite functional assessment (of two or more tests) to demonstrate better correlation with structural changes. The correlation of anatomical features like central subfield thickness, epiretinal membrane, intraretinal fluid, and subretinal fluid volumes with visual acuity outcomes remain uncertain.

conclusionThis consensus supports the need to develop a composite assessment to improve patient care. Utilising contrast sensitivity, distance and near low luminance, and novel patient-reported outcome measures may improve patient-centric assessments to better understand the patient's quality of life and functional experience.

Indexed as

Contrast sensitivityDelphi methodDiabetic macular oedemaDiabetic retinopathyQuality of lifeVisual acuity

Identifiers

PMID41746594
PMCPMC12976320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.