Evidence map›Paper›PMID 41746525›Full record

ReviewMolecular biology reports2026

Mechanisms of angiopoietin-like protein 7 regulation and therapeutic potential in tumors.

Xiaoxiao Fan, Wenxin Zheng, Xianglong Tian, Xiaolin Wu

Abstract readReview
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In one paragraph

Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoxiao FanDepartment of Neurocell Biology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, 154000, China.
Wenxin ZhengDepartment of Neurocell Biology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, 154000, China.
Xianglong TianCentral Laboratory, Shanghai Eighth People's Hospital, Shanghai, 200233, China.
Xiaolin WuDepartment of Neurocell Biology, School of Basic Medical Sciences, Jiamusi University, Jiamusi, 154000, China. wuxiaolin999@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiopoietin-like 7 (ANGPTL7) is a member of the angiopoietin-like protein family, which plays critical physiological roles in angiogenesis, tissue homeostasis maintenance, inflammatory signaling, glucose metabolism and lipid metabolism. Meanwhile, ANGPTL7 is also implicated in the regulation of numerous pathological processes and disease development. In recent years, several studies have demonstrated that ANGPTL7 is differentially expressed in various types of tumors and it may regulate tumourigenesis, tumor angiogenesis, invasion, and metastasis through diverse mechanisms. Additionally, ANGPTL7 has been implicated in the diagnosis and prognosis of tumor patients, suggesting its potential as a novel biomarker for tumor prediction. In this review, we provide a comprehensive overview of the structure and function of ANGPTL7, as well as its role and underlying mechanisms in tumor development. Furthermore, we discuss potential future research directions and clinical applications of ANGPTL7 in oncology.

Indexed as

Angiopoietin-like ProteinsNeoplasmsAngiopoietin-Like Protein 7AnimalsBiomarkers, TumorCarcinogenesisGene Expression Regulation, NeoplasticHumansNeovascularization, PathologicSignal TransductionAngiopoietin-Like Protein 7Angiopoietin-like ProteinsANGPTL7 protein, humanBiomarkers, TumorAngiopoietin ⁃ like 7(ANGPTL7)Tumor angiogenesisTumorigenesisTumor metastasis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.