Evidence map›Paper›PMID 41746468›Full record

ArticleAIDS and behavior2026

Association between Levels of Alcohol Use, Perceived HIV Risk, and Untreated HIV Among Persons at Alcohol-Serving Venues in Kenya and Uganda.

Brian Beesiga, Janice Litunya, Joy Z Nakato, Jaquiline A Agola, Kara Marson, Wafula E Mugoma, Pius Agaba, Jennifer Temple, Carol S Camlin, Starley B Shade and 11 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Brian BeesigaInfectious Diseases Research Collaboration (IDRC), Plot 2C Nakasero Hill road, Kampala, Uganda. beesigab@gmail.com.ORCID http://orcid.org/0000-0001-5927-8857
Janice LitunyaKenya Medical Research Institute, Nairobi, Kenya.
Joy Z NakatoSchool of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Jaquiline A AgolaKenya Medical Research Institute, Nairobi, Kenya.
Kara MarsonUniversity of California San Francisco, San Francisco, CA, USA.
Wafula E MugomaKenya Medical Research Institute, Nairobi, Kenya.
Pius AgabaInfectious Diseases Research Collaboration (IDRC), Plot 2C Nakasero Hill road, Kampala, Uganda.
Jennifer TempleUniversity of California San Francisco, San Francisco, CA, USA.
Carol S CamlinUniversity of California San Francisco, San Francisco, CA, USA.
Starley B ShadeUniversity of California San Francisco, San Francisco, CA, USA.
Sarah E Woolf-KingDepartment of Psychology, Syracuse University, Syracuse, NY, USA.
Judith A HahnUniversity of California San Francisco, San Francisco, CA, USA.
Elijah KakandeInfectious Diseases Research Collaboration (IDRC), Plot 2C Nakasero Hill road, Kampala, Uganda.
Jane KabamiInfectious Diseases Research Collaboration (IDRC), Plot 2C Nakasero Hill road, Kampala, Uganda.
Maya L PetersenSchool of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Diane V HavlirUniversity of California San Francisco, San Francisco, CA, USA.
Laura B BalzerSchool of Public Health, University of California, Berkeley, Berkeley, CA, USA.
James AyiekoKenya Medical Research Institute, Nairobi, Kenya.
Moses R KamyaInfectious Diseases Research Collaboration (IDRC), Plot 2C Nakasero Hill road, Kampala, Uganda.
Gabriel ChamieUniversity of California San Francisco, San Francisco, CA, USA.
OPAL-East Africa trial team

Funding

Innovative strategies to promote biomedical HIV prevention uptake and retention among high-risk adults at drinking venues in Kenya and UgandaR01AA030464 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Gabriel Chamie · 2022 to 2026
$3.0M
Mentorship in patient-oriented research to optimize community-based HIV prevention for adults at high-risk of HIV at alcohol drinking venues in East AfricaK24AA031211 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Gabriel Chamie · 2023 to 2026
$785k
NIAAA NIH HHS 1R01AA030464-01NIAAA NIH HHS K24 AA031211NIAAA NIH HHS R01 AA030464NIH HHS K24AA031211
6 · The paper itself

Abstract

Alcohol-serving venues in East Africa are high-risk environments for HIV transmission but few studies in sub-Saharan Africa (SSA) have examined perceived HIV risk and sexual risk behaviors by alcohol use levels on a broader population of persons at alcohol-serving venues in the era of biomedical HIV prevention. We conducted a cross-sectional analysis of adults (≥ 18 years) at alcohol-serving venues in eight communities (~ 10,000 residents/community) in rural western Kenya and southwestern Uganda. We distributed recruitment cards to patrons and workers and invited them for free HIV screening at nearby health facilities, with same-day initiation of HIV pre- or post-exposure prophylaxis or antiretroviral therapy (ART) if eligible. Using generalized estimating equations with adjustment for age, sex, and country, we assessed whether increasing levels of alcohol use, as measured by the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C), categorized as no/low use (< 4 for men, < 3 for women), medium use (4-5 for men, 3-5 for women), high use (6-7), and very high use (≥ 8) were predictive of perceived HIV risk (current or anticipated in the next three months) and four HIV-risk factors (i.e., sex with a partner with HIV or unknown HIV status, multiple sexual partners, transactional sex, and sexually transmitted infections) among persons without HIV. We also evaluated the association between AUDIT-C levels and untreated HIV (defined as newly diagnosed or previously diagnosed but out of care for ≥ 6 months) among persons with HIV and between AUDIT-C levels and HIV-risk factors among persons with untreated HIV. We distributed 9,375 recruitment cards at 480 venues: 7,744 (83%) adults participated in screening at health facilities (median age 34 years; 38% women; 91% patrons). Overall, 4,107 (53%) reported unhealthy alcohol use: 26% medium, 11% high, 16% very high. Of 6,124 (79%) persons who tested HIV-negative, 2,285 (37%) reported perceived HIV risk. Increasing alcohol use was significantly associated with higher odds of perceived HIV risk (medium use: adjusted odds ratio (aOR) = 1.36, 95% CI: 1.17-1.58, p < 0.001; high: aOR = 2.06, 95%CI: 1.71-2.47, p < 0.001; and very high: aOR = 2.07, 95%CI: 1.74-2.47, p < 0.001; vs. no/low alcohol use) as well as sexual risk factors. Of 1,620 (21%) PWH, 219 (14%) had untreated HIV: 141 (9%) newly diagnosed; 78 (5%) previously diagnosed, not on ART. Increasing levels of alcohol use were not associated with untreated HIV. Our findings highlight the ongoing need for interventions to reduce alcohol use and improve engagement in biomedical HIV prevention and treatment among adults at alcohol-serving venues in East Africa.

Indexed as

Alcohol DrinkingHIV InfectionsSexual BehaviorAdolescentAdultCross-Sectional StudiesDrinking EstablishmentsFemaleHumansKenyaMaleMiddle AgedRisk FactorsRisk-TakingRural PopulationUgandaAlcoholAlcohol-serving venuesHIV riskUntreated HIV

Identifiers

PMID41746468
PMCPMC13131387

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.