Evidence map›Paper›PMID 41746433›Full record

ArticleFunctional & integrative genomics2026

The complete chloroplast genome sequence of Typhonium flagelliforme, an anti-cancer medicinal plant: genome structure, comparative and phylogenetic relationship analysis within Araceae.

Devit Purwoko, Arief Priyadi, Siti Zulaeha, Gemilang Rahmadara, Suparjo, Teuku Tajuddin, Ani Kurniawati, Sobir

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Article in Functional & integrative genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Devit PurwokoResearch Center for Applied Botany, Research Organization for Life Sciences and Environment, BRIN, Science and Technology Area of Soekarno, Cibinong, Bogor, West Java, 16911, Indonesia. devit.purwoko@brin.go.id.ORCID http://orcid.org/0000-0002-9551-8528
Arief PriyadiResearch Center for Applied Botany, Research Organization for Life Sciences and Environment, BRIN, Science and Technology Area of Soekarno, Cibinong, Bogor, West Java, 16911, Indonesia.
Siti ZulaehaResearch Center for Applied Botany, Research Organization for Life Sciences and Environment, BRIN, Science and Technology Area of Soekarno, Cibinong, Bogor, West Java, 16911, Indonesia.
Gemilang RahmadaraResearch Center for Applied Botany, Research Organization for Life Sciences and Environment, BRIN, Science and Technology Area of Soekarno, Cibinong, Bogor, West Java, 16911, Indonesia.
SuparjoResearch Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, BRIN. Science and Technology Area of Soekarno, Cibinong, Bogor, West Java, 16911, Indonesia.
Teuku TajuddinResearch Center for Applied Botany, Research Organization for Life Sciences and Environment, BRIN, Science and Technology Area of Soekarno, Cibinong, Bogor, West Java, 16911, Indonesia.
Ani KurniawatiDepartment of Agronomy and Horticulture, Faculty of Agriculture, IPB University, Bogor, Indonesia.
SobirDepartment of Agronomy and Horticulture, Faculty of Agriculture, IPB University, Bogor, Indonesia.

Funding

Join Collaboration Inhouse Biological and Environmental Research Organization BRIN Program B-1779/III.5/PR.03.06/7/2025RIIM Collaborative Platform Biology Biomolecular Structure Biodiversity 2657/III.5/FR.06.00/6/2024
6 · The paper itself

Abstract

Typhonium flagelliforme, an Indonesian endemic medicinal species from the Araceae family, has attracted growing scientific interest due to its notable anticancer potential. Recognized as a valuable genetic resource, this species offers promising prospects for future breeding and biotechnological applications. In this study, we report the first complete chloroplast (cp.) genome of T. flagelliforme. The chloroplast genome spans 167,120 bp and displays the canonical quadripartite organization, comprising a large single-copy (LSC) region of 89,453 bp, a small single-copy (SSC) region of 14,524 bp, and two inverted repeats (IRs) of 31,573 bp each. Genome annotation recovered 130 genes, including 87 protein-coding genes, 8 rRNA genes, and 35 tRNA genes. We identified 102 simple sequence repeats (SSRs), with mononucleotide repeats representing the majority (86%). Phylogenetic reconstruction highlights the genetic coherence of T. flagelliforme while clearly separating it from other Typhonium species, providing further resolution of evolutionary relationships within the Araceae. Collectively, these genomic insights not only enhance our understanding of T. flagelliforme’s evolutionary context but also contribute foundational knowledge for future taxonomic, phylogenetic, and conservation studies within the genus.

Indexed as

AraceaeGenome, ChloroplastPhylogenyPlants, MedicinalMicrosatellite RepeatsChloroplast genomeComparative analysisMedicinal plantPhylogenyRodent tubber

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.