Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
CanRestoreFunction: Cancer-related fatigue management eHealth intervention- a pilot pragmatic randomized-control trial.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05868187 (CanRestoreFunction), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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CanRestoreFunction: Cancer-Related Fatigue Management
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Abstract
purposeTo investigate the effect of an 8-week multi-modal eHealth cancer-related fatigue intervention in women with breast cancer. eHealth included remote education, individualized exercise, and weekly problem-solving sessions. Primary outcomes were recruitment/retention and cancer-related fatigue level. Quality of life was a secondary aim.
methodsWomen with Stage 0-3 breast cancer between 18-70 years who scored ≥ 4/10 on the One-Item Fatigue Scale, completed chemotherapy and/or radiation within 5 years, and did not have chronic fatigue, were randomly assigned to eHealth intervention (eHealth) (n = 18) or control (n = 24). Cancer-related fatigue and quality of life were measured before and after intervention using the Brief Fatigue Inventory and the Functional Assessment Cancer Therapy-General.
resultsSocial media was an effective way to recruit participants into this study; however, more participants in the eHealth group dropped out than the control group. Both groups' fatigue scores significantly decreased over time (p = 0.001). eHealth decreases in fatigue reached a minimally clinically important difference (2.25), but control did not (1.3). Quality of life significantly improved in the eHealth group compared to the control (p = 0.03).
conclusionMulti-modal cancer-related fatigue eHealth intervention appears to clinically reduce fatigue and improve quality of life among women with breast cancer. US Clinical Trial Register NCT05868187. Date registered: 2-7-2023. www.clinicalgrials.gov.
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