Evidence map›Paper›PMID 41746426›Full record

SynthesisInternational journal of biometeorology2026

Evidence-based balneotherapy in Hungary. Updated systematic review and meta-analysis of the Hungarian clinical trials.

Tamas Bender, Katalin Hodosi, Ildikó Katalin Tefner

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International journal of biometeorology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tamas BenderPolyclinic of the Hospitaller Brothers of St. John of God, Budapest, Hungary. bender.tamas@t-online.hu.ORCID http://orcid.org/0000-0003-1170-3767
Katalin HodosiFaculty of Medicine, University of Debrecen, Debrecen, Hungary.
Ildikó Katalin TefnerDepartment of Rheumatology, Saint Cosmas Health Centre of Joseph Town, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2014 the authors published a review and meta-analysis on the effectiveness of balneotherapy in Hungary based on articles by Hungarian authors issued until 2012. Now they prepared a new review and meta-analysis based on the updated database of the Hungarian articles published after 2012. A total of 18 articles were included in the new meta-analysis; with a subset having been previously incorporated in the earlier analyses. In such a way the results became more convincing. Regarding the updated systematic review (period: 2012–2025), the number of papers was 14. Regarding the meta-analysis (period: 1989–2025), the number of papers was 18 (8 + 10 = 18). The meta-analysis showed a significant reduction of pain at rest and pain on load evaluated by visual analogue scale (VAS) score and of the quality of life evaluated by the EuroQol-5D (EQ-5D) questionnaire and indexed by the EQ-VAS and the EQ-5D index. Even accounting for the heterogeneity of the studies, which is a source of bias, based on the results we can say the Hungarian studies’ results are promising regarding the positive effect of balneotherapy, especially in the treatment of degenerative locomotor diseases.

Indexed as

BalneologyClinical Trials as TopicEvidence-Based MedicineHumansHungaryQuality of LifeBalneotherapyHungaryMeta-analysisSystematic review

Identifiers

PMID41746426
PMCPMC12945968

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.