Evidence map›Paper›PMID 41746389›Full record

ArticleLangenbeck's archives of surgery2026

Is surgery with curative intent feasible in old and very old patients with non-small cell lung cancer? - Experience of a certified lung cancer center over one decade.

Julia Zimmermann, Julia Walter, Nicole Samm, Fuad Damirov, Niels Reinmuth, Diego Kauffmann-Gerrero, Rudolf A Hatz, Amanda Tufman, Christian P Schneider

Abstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia ZimmermannDivision of Thoracic Surgery, LMU University Hospital Munich and Asklepios Lung Clinic Gauting, Munich, Germany. Julia.Zimmermann@med.uni-muenchen.de.ORCID http://orcid.org/0000-0002-9806-3397
Julia WalterDepartment of Internal Medicine V, LMU University Hospital, Munich, Germany.
Nicole SammDivision of Thoracic Surgery, LMU University Hospital Munich and Asklepios Lung Clinic Gauting, Munich, Germany.
Fuad DamirovDivision of Thoracic Surgery, LMU University Hospital Munich and Asklepios Lung Clinic Gauting, Munich, Germany.
Niels ReinmuthDepartment of Thoracic Oncology, Asklepios Lung Clinic Gauting, Gauting, Germany.
Diego Kauffmann-GerreroDepartment of Internal Medicine V, LMU University Hospital, Munich, Germany.
Rudolf A HatzDivision of Thoracic Surgery, LMU University Hospital Munich and Asklepios Lung Clinic Gauting, Munich, Germany.
Amanda TufmanDepartment of Internal Medicine V, LMU University Hospital, Munich, Germany.
Christian P SchneiderDivision of Thoracic Surgery, LMU University Hospital Munich and Asklepios Lung Clinic Gauting, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNon-small cell lung cancer (NSCLC) accounts for 80% of all lung cancers and, like most other cancers, is a disease of advanced age. This study analyzed the question of whether surgical treatment for non-small cell lung cancer (NSCLC) in elderly patients is acceptable in all operable stages with curative intent.

methodsIn this retrospective analysis, we used data of all NSCLC patients aged over 60 who underwent lobectomy at the Lung Cancer Centre Munich between 2011–2020 and divided them into four groups in ascending order of age. We performed Kaplan–Meier survival analysis and multivariate Cox regression to compare progression-free survival (PFS) and overall survival (OS) between the age groups. To compare numerical outcomes between the age groups we used analysis of variance (ANOVA), and Chi2-test for categorical outcomes.

resultsOf 1680 patients undergoing lobectomy, 1221 met our inclusion criteria. It was found that the length of hospital stay increased with advanced age and was significantly longer in older patients (p < 0.001). Although the older patients had more comorbidities, only cardiac arrhythmias occurred significantly more often in the postoperative phase (p = 0.02). Kaplan–Meier survival analysis and multivariate Cox regression analysis showed significantly poorer OS for patients aged over 80 compared to patients aged between 60 to 69. PFS was not significantly associated with age.

conclusionSurgery with curative intent is feasible in old and very old patients with NSCLC and the oncological outcome is comparable. However, we recommend individual selection in view of patient age.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPneumonectomyAgedAged, 80 and overAge FactorsFeasibility StudiesFemaleGermanyHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesSurvival RateTreatment OutcomeElderly patientsNon-small cell lung cancerOverall survivalProgression-free survivalSurgical treatment

Identifiers

PMID41746389
PMCPMC12975854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.