Evidence map›Paper›PMID 41746179›Full record

ArticleInorganic chemistry2026

Ligand Radicals Tune LPMO Activity in Model Complex.

Caterina G C Marques Netto, Ritika Pandey, Caio Bezerra de Castro, Larissa Moreno, Millena Pereira Ferreira, Lullie Gomes Rodrigues, Walber Gonçalves Guimaraes, João Honorato de Araujo-Neto, Gabrielle Conciani, R Brian Dyer and 4 more

Abstract read
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In one paragraph

Article in Inorganic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Caterina G C Marques NettoDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States of America.ORCID 0000-0002-3285-4129
Ritika PandeyDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States of America.
Caio Bezerra de CastroDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.
Larissa MorenoDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.
Millena Pereira FerreiraDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.
Lullie Gomes RodriguesDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.ORCID 0000-0001-5402-8015
Walber Gonçalves GuimaraesDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.
João Honorato de Araujo-NetoInstituto de Química, Departamento de Química Fundamental, Universidade de São Paulo (USP), Av. Prof. Dr. Lineu Prestes, 748, São Paulo, SP CEP 05513-970, Brazil.ORCID 0000-0002-1127-6083
Gabrielle ConcianiDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.ORCID 0009-0007-5155-6112
R Brian DyerDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States of America.ORCID 0000-0002-0090-7580
Sergio A V JannuzziMax Planck Institute for Chemical Energy Conversion, Stiftstr. 34-36, Mülheim an der Ruhr 45470, Germany.ORCID 0000-0001-7406-6633
André F de MouraDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.
Dulce H Ferreira de SouzaDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rod. Washinton Luiz, s/n km 235, São Carlos, SP CEP 13565905, Brazil.
Otaciro R NascimentoInstituto de Física de São Carlos, Universidade de São Paulo (USP), Av. Joao Dagnone, 1100, Sao Carlos, SP CEP 13563-120, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radicals are essential to the catalytic chemistry of metalloenzymes, enabling reactivity and self-protection through controlled redox processes. In copper-dependent LPMOs, amino acid radicals mediate oxidative transformations via hole hopping. However, the generation and role of ligand-centered radicals in synthetic copper models remain poorly understood. Here we show that an l-proline-based N,N,O,O-coordinated copper complex (

Indexed as

Coordination ComplexesMixed Function OxygenasesCatalysisCopperFree RadicalsLigandsModels, MolecularMolecular StructureOxidation-ReductionProlineCoordination ComplexesCopperFree RadicalsLigandsMixed Function OxygenasesProline

Identifiers

PMID41746179
PMCPMC12997159

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.