ArticleExperimental physiology2026
Identification of the individual cardiac contraction threshold during high-frame-rate stress echocardiography.
Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Identification of the individual cardiac contraction threshold during high-frame-rate stress echocardiography.Experimental physiology · 2026Article
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5 authors.
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Abstract
The clinical assessment of cardiovascular function during exercise using stress echocardiography is essential for accurate cardiac diagnosis. However, normal limitations of cardiac deformation responses to increasing physical exertion remain poorly understood. We introduce the individual cardiac contraction threshold (iCarT) as a novel marker of mechanical cardiac limitation and examine its relationship to standard cardiovascular measures.High-frame-rate (121-276 frames/s) exercise echocardiography was performed during stepwise cardiopulmonary exercise testing on a recumbent cycle ergometer in 19 healthy, recreationally active adults. Visit 1 was used to individualie exercise protocols, applied in Visit 2. Left ventricular (LV) peak twist, longitudinal strain (LS), and apical circumferential strain (ACS) were assessed at each exercise stage. Polynomial curve fitting was used to identify plateaus in deformation parameters. iCarT was defined as the relative heart rate, expressed as a percentage of maximum heart rate (% HR
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