Evidence map›Paper›PMID 41746095›Full record

ArticleVaccines2026

Reaching Never- and Incompletely-Vaccinated Children with Routine Immunization: A Proof-of-Concept Activity Using Geo-Referenced Microplans in Two Health Zones in Maniema Province, Democratic Republic of the Congo.

Mary M Alleman, Affaud Anais Tanon, Emmanuel Rukengwa, Kevin Tschirhart, Christ Lendo, Merveille Balepukayi, Grace Koko Cishugi, Eddy Balume Shaboya, Chuku Mburugu, Gloire Chasinga and 15 more

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Mary M AllemanGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-8591-7787
Affaud Anais TanonGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Emmanuel RukengwaGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.
Kevin TschirhartGRID3, New York, NY 10017, USA.
Christ LendoGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.ORCID 0009-0006-3669-4720
Merveille BalepukayiGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.
Grace Koko CishugiGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.
Eddy Balume ShaboyaGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.
Chuku MburuguGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.
Gloire ChasingaGRID3, Kinshasa BP 7248 Kin 1, Democratic Republic of the Congo.
Amy Louise LangDRT Strategies, Arlington, VA 22209, USA.ORCID 0009-0001-5039-1914
Katherine SchwenkGeospatial Research, Analysis and Services Program (GRASP), Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Roger WidmerNovel-t, 1214 Geneva, Switzerland.ORCID 0009-0001-0223-3719
Stéphane VouillamozNovel-t, 1214 Geneva, Switzerland.
Jean Jacques Kanyaka BiduayaBizzell, New Carrollton, MD 20785, USA.
Alain MagazaniAfrican Field Epidemiology Network (AFENET), Regional Coordination Office for the Central and Indian Ocean Francophone Region, Kinshasa 01207, Democratic Republic of the Congo.
John KaoziExpanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.
Generose Matunda SumailiExpanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.
Serge SukaniExpanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.
Dolla Ngwanga LapabaExpanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.
Kimberly E BonnerGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-6942-4050
Robert T PerryGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-7322-7703
Jean Crispin MukendiExpanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.
Aimé Cikomola Mwana Wa BeneExpanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.ORCID 0000-0002-7016-8197
Paul LameMashako Plan, Expanded Programme on Immunization, Ministry of Public Health, Hygiene, and Prevention, Kinshasa 01206, Democratic Republic of the Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe Democratic Republic of the Congo (DRC) has a history of low coverage (<50%) with all first-year-of-life vaccines for children aged 12-23 months, resulting in frequent outbreaks of vaccine-preventable diseases. In response, the DRC's Expanded Program on Immunization (EPI) is applying innovations to improve vaccination coverage, including using geospatial data to inform vaccination planning (geo-referenced microplans). This report describes a proof of concept to geo-locate, by locality of residence, never-vaccinated children (NVC) or incompletely vaccinated children (IVC); use those data to prepare geo-referenced microplans for rounds of Periodic Intensification of Routine Immunization (PIRIs); and implement the PIRIs.

methodsIn 2022, in Kindu and Kibombo Health Zones (HZs), Maniema Province, DRC, children aged 0-23 months were enumerated with inquiries about their vaccination status and reasons for non-vaccination by locality of residence. The enumeration was coupled with the collection of the localities' geographic coordinates, facilitating the spatial illustration of estimated proportions of NVC by locality. Coordinates for HZ and health area (HA) landmarks and borders were also collected. We created maps that informed geo-referenced PIRI microplans, placing an emphasis on deploying vaccination teams to localities with high proportions of NVC, especially those in remote and riverine locations. To account for inclusion of children aged up to 59 months in the PIRIs, enumeration data were extrapolated to estimate the numbers of NVC and IVC in this wider age range. Volunteers mobilized communities for the PIRIs, HA staff vaccinated age-eligible children, and vaccination teams were geographically tracked.

resultsIn Kindu, 29,837 children aged 0-23 months were enumerated in 430 localities; among them, 38% were NVC and 6% IVC. In Kibombo, 9582 children aged 0-23 months were enumerated in 168 localities; among them, 50% were NVC and 16% IVC. In both HZs, reasons for never vaccination were primarily associated with knowledge- or belief-related factors, while reasons for incomplete vaccination were associated with access-related factors. Between HAs and localities, there was heterogeneity in the proportions of NVC and IVC and in the reasons for non-vaccination. The numbers of NVC and IVC aged 0-59 months were estimated at 28,220 and 4613 in Kindu and 12,038 and 3785 in Kibombo. Approximately 2000 health staff and community volunteers were engaged for implementation of each of the three PIRIs. The number of children vaccinated during the three PIRIs ranged from 15,500 to 26,500 and from 10,500 to 15,500 in Kindu and Kibombo, respectively. Data suggest that vaccinated children originated from >90% of localities identified during the cartography. Tracking data showed that vaccination teams visited localities with high proportions of NVC, including those that were remote and riverine.

conclusionsGeo-referenced microplanning with engagement of health staff and communities succeeded in vaccinating at least 40,000 children who were not routinely benefiting from health services in two HZs in the DRC; similar innovative strategies could be considered elsewhere. Applying new technologies to existing microplanning strategies can enhance their success.

Indexed as

Democratic Republic of the Congogeo-referenced microplanninggeo-spatial analysisincompletely-vaccinated childrenmicroplanningnever-vaccinated childrennon-vaccinationperiodic intensification of routine immunizationreasons for non-vaccinationroutine immunizationzero-dose children

Identifiers

PMID41746095
PMCPMC12945245

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.