Evidence map›Paper›PMID 41746078›Full record

ArticleVaccines2026

Non-Clinical Safety of GRAd Vector-Based COVID-19 and HIV Vaccines Supports a Platform Regulatory Approach.

Reji Paalangara, Stephanie Gohin, Alexis Menard, Charlotte Amy, Wahiba Berrabah, Alexandra Rogue, Matthew A Getz, Aljawharah Alrubayyi, Simone Battella, Angelo Raggioli and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Reji PaalangaraInternational AIDS Vaccine Initiative (IAVI), New York, NY 10004, USA.ORCID 0009-0003-0008-3475
Stephanie GohinCharles River Laboratories Evreux, 27930 Miserey, France.
Alexis MenardCharles River Laboratories Evreux, 27930 Miserey, France.
Charlotte AmyCharles River Laboratories Evreux, 27930 Miserey, France.
Wahiba BerrabahCharles River Laboratories Evreux, 27930 Miserey, France.
Alexandra RogueCharles River Laboratories Evreux, 27930 Miserey, France.
Matthew A GetzRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0002-4172-2187
Aljawharah AlrubayyiRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.
Simone BattellaReiThera Srl, 00128 Rome, Italy.
Angelo RaggioliReiThera Srl, 00128 Rome, Italy.ORCID 0000-0002-6748-0307
Michela GentileReiThera Srl, 00128 Rome, Italy.
Anthea Di RitaReiThera Srl, 00128 Rome, Italy.
Alessia NotoReiThera Srl, 00128 Rome, Italy.
Giuseppina MiselliReiThera Srl, 00128 Rome, Italy.
Fabiana GrazioliReiThera Srl, 00128 Rome, Italy.
Federico NapolitanoReiThera Srl, 00128 Rome, Italy.
Dhurata SowcikInternational AIDS Vaccine Initiative (IAVI), New York, NY 10004, USA.
Marco SorianiReiThera Srl, 00128 Rome, Italy.ORCID 0000-0002-9752-5844
Benjamin ChmielewskiInternational AIDS Vaccine Initiative (IAVI), New York, NY 10004, USA.ORCID 0009-0009-4470-218X
Lebohang MolifeInternational AIDS Vaccine Initiative (IAVI), New York, NY 10004, USA.
Vincent Muturi-KioiInternational AIDS Vaccine Initiative (IAVI), New York, NY 10004, USA.ORCID 0000-0003-1620-3999
Azure Tariro MakadzangeMutala Trust, Harare, Zimbabwe.ORCID 0000-0001-5330-1470
Gaurav D GaihaRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.ORCID 0000-0001-6875-4472
Philippe AncianCharles River Laboratories Evreux, 27930 Miserey, France.ORCID 0000-0003-0905-4745
Jim AcklandGlobal BioSolutions, Vermont, VIC 3133, Australia.
Antonella FolgoriReiThera Srl, 00128 Rome, Italy.
Stefano CollocaReiThera Srl, 00128 Rome, Italy.
Stefania CaponeReiThera Srl, 00128 Rome, Italy.ORCID 0000-0002-2272-120X

Funding

Gates Foundation INV-059646; INV-008696; INV-064567; INV-007375; INV-065025Italian Ministry of Research N/ARegione Lazio N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biodistributionCOVID-19gorilla adenovirusHIVnon-clinical safetytoxicityvaccine platformviral vectors

Identifiers

PMID41746078
PMCPMC12944892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.