Evidence map›Paper›PMID 41746064›Full record

ArticleVaccines2026

Development and Evaluation of Immunoprotective Efficacy of Membrane Protein Vaccine Against Scuticociliatosis.

Qingmeihui Sun, Bingchen Wu, Yaoqi Ao, Xiaoyu Meng, Xiaohang Wang, Ruijun Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingmeihui SunLiaoning Key Laboratory of Pufferfish Breeding and Culture, Liaoning Key Laboratory of Marine Animal Immunology, Dalian Key Laboratory of Marine Animal Disease Control and Prevention, College of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Bingchen WuLiaoning Key Laboratory of Pufferfish Breeding and Culture, Liaoning Key Laboratory of Marine Animal Immunology, Dalian Key Laboratory of Marine Animal Disease Control and Prevention, College of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Yaoqi AoLiaoning Key Laboratory of Pufferfish Breeding and Culture, Liaoning Key Laboratory of Marine Animal Immunology, Dalian Key Laboratory of Marine Animal Disease Control and Prevention, College of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Xiaoyu MengLiaoning Key Laboratory of Pufferfish Breeding and Culture, Liaoning Key Laboratory of Marine Animal Immunology, Dalian Key Laboratory of Marine Animal Disease Control and Prevention, College of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Xiaohang WangCenter for Animal Disease Control and Prevention in Shenyang City, Shenyang 110034, China.
Ruijun LiLiaoning Key Laboratory of Pufferfish Breeding and Culture, Liaoning Key Laboratory of Marine Animal Immunology, Dalian Key Laboratory of Marine Animal Disease Control and Prevention, College of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0001-8385-1748

Funding

National Key Research and Development Program of China 2023YFC2812102
6 · The paper itself

Abstract

objectiveTo develop a novel and efficient vaccine for controlling scuticociliatosis in turbot (

methodsThe immunoprotective efficacy and underlying molecular mechanisms of the vaccine were systematically evaluated through immunization-challenge experiments, immune parameter detection, and transcriptomic analysis.

resultsResults showed that the serum IgM level in turbot immunized with the membrane protein vaccine reached its peak one week after the second immunization, which was significantly higher than that in the control group and the whole-cell protein vaccine group (

conclusionsThis study successfully developed a

Indexed as

immunitymembrane proteinscuticociliate vaccineturbot (Scophthalmus maximus)

Identifiers

PMID41746064
PMCPMC12944841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.