Evidence map›Paper›PMID 41746043›Full record

ArticleVaccines2026

Long-Term Protective Immune Responses Induced by rBCG-RBD/rRBD Heterologous Prime/Boost Immunization Strategy: Fusion of RBD-Wuhan with LTB Adjuvant Induces Cross-Reactivity with SARS-CoV-2 Variant Omicron.

Giana Carla Gaboardi, Monalisa Martins Trentini, Alex Issamu Kanno, Luana Moraes, Arthur Daniel Januzzi, Lennon Ramos Pereira, Greicy Brisa Malaquias Dias, Luciano Fernandes Huergo, Sergio C Oliveira, André Bafica and 1 more

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giana Carla GaboardiLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0001-5153-5468
Monalisa Martins TrentiniLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-3207-8967
Alex Issamu KannoLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-4731-1493
Luana MoraesLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0001-9701-7199
Arthur Daniel JanuzziLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-9513-3791
Lennon Ramos PereiraLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-8070-7772
Greicy Brisa Malaquias DiasLaboratory of Immunobiology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil.ORCID 0000-0002-6901-4908
Luciano Fernandes HuergoUniversidade Federal do Paraná, Setor Litoral, Matinhos 83260-000, Brazil.ORCID 0000-0002-7587-9510
Sergio C OliveiraDepartamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo 05508-060, Brazil.ORCID 0000-0003-4062-5577
André BaficaLaboratory of Immunobiology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil.ORCID 0000-0002-5148-600X
Luciana Cezar de Cerqueira LeiteLaboratório de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0003-0156-1312

Funding

Brucella survival strategy requires endoplasmic reticulum restructuring and interferes with innate immunityR01AI116453 · NIAID · FOUNDATION FOR RESEARCH DEVELOPMENT · PI BARBER, GLEN N, OLIVEIRA, SERGIO C · 2016 to 2025
$1.4M
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 406703/2022-1Fundação de Amparo à Pesquisa no Estado de São Paulo (FAPESP) 2018/24832-6NIAID NIH HHS R01 AI116453
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cross-protection against variantshumoral and cellular immune responsesneutralizing antibodiesrecombinant BCGSARS-CoV-2

Identifiers

PMID41746043
PMCPMC12944924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.