Evidence map›Paper›PMID 41746002›Full record

ReviewVeterinary sciences2026

The Role of Five Key Minerals (Cu, Se, Zn, Co, Fe) in Reproductive Function of Female Cattle: Current Insights and Future Directions.

Beiyao Wang, Xinlin Li, Zimo Zhou, Yanqiu Zhu, Zhicai Zuo, Hongrui Guo

Abstract readReview
In one paragraph

Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Impact of Nutrition on Embryo Production in Cattle: Mechanistic Insights.Animals : an open access journal from MDPI · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beiyao WangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Xinlin LiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Zimo ZhouCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Yanqiu ZhuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Zhicai ZuoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Hongrui GuoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-3992-3529

Funding

China Agriculture Research System of MOF and MARA Beef Cattle/Yak, CARS-37Innovative Team for Beef Cattle Low-Carbon Production 2022-2024National key research and development project 2022YFD1601600
6 · The paper itself

Abstract

Reproductive efficiency in female cattle is significantly influenced by micronutrient status, particularly the availability and balance of essential trace minerals. Selenium, copper, zinc, cobalt, and iron serve as critical components of enzymatic systems, antioxidant defense networks, hormone synthesis, and cellular metabolism, collectively sustaining reproductive health. This review integrates current research evidence on the physiological functions and molecular mechanisms through which these five trace minerals regulate reproductive performance in female cattle, with a specific focus on iron-an often overlooked element-highlighting the novelty of this synthesis. Both deficiency and excess of these minerals impair key reproductive outcomes such as estrous cyclicity, conception rate, and embryonic survival. Furthermore, complex interactions among minerals influence their bioavailability and physiological responses. Advances in mineral supplementation strategies, particularly the application of organic minerals and precision feeding technologies, offer promising solutions to improve reproductive performance. Elucidating these interrelationships provides a theoretical foundation for optimizing trace mineral nutrition, thereby enhancing female cattle fertility, reducing metabolic disorders and promoting the sustainable development of beef and dairy industries.

Indexed as

female cattlefertilitymineral nutritionoxidative stressreproductive physiology

Identifiers

PMID41746002
PMCPMC12945088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.