Evidence map›Paper›PMID 41745995›Full record

ArticleVeterinary sciences2026

Left Atrioventricular Coupling Index: An Echocardiographic Index of Atrioventricular Dysfunction in Dogs with Myxomatous Mitral Valve Disease.

Federica Valeri, Francesco Porciello, Mark Rishniw, Simone Cupido, Maria Cicogna, Andrea Corda, Domenico Caivano

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federica ValeriDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0009-0005-7940-8416
Francesco PorcielloDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-6229-3158
Mark RishniwVeterinary Information Network, Davis, CA 95616, USA.
Simone CupidoDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Maria CicognaDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Andrea CordaDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9771-4143
Domenico CaivanoDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-8540-4853

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The close physiological relationship between the left atrium (LA) and left ventricle (LV) suggests that an index assessing both the cardiac chambers simultaneously could provide useful information about disease severity. Consequently, investigators have proposed the atrioventricular coupling index (LACi) and demonstrated its utility in predicting the likelihood of atrial fibrillation, heart failure, and other cardiovascular events in humans. No studies have been reported in veterinary medicine. Therefore, we measured the LACi in healthy dogs and dogs affected by myxomatous mitral valve disease (MMVD). Two hundred and thirty-three dogs (105 healthy dogs and 128 dogs with MMVD) were retrospectively included in the study. The LACi (LA volume/LV volume × 100) at LV end-diastole (LACi-ED) and LV end-systole (LACi-ES) of each dog was measured using a monoplane Simpson's Method of Discs from the left apical four-chamber view. In healthy dogs, LACi-ED and LACi-ES showed no relationship with bodyweight, heart rate and age (R

Indexed as

canineechocardiographyleft atriumleft ventriclemitral valve disease

Identifiers

PMID41745995
PMCPMC12945114

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.