Evidence map›Paper›PMID 41745986›Full record

ArticleVeterinary sciences2026

Preparation of a Lyophilized Bovine Milk Reference Material for Quality Control of Amoxicillin Detection.

Shulin Wei, Wei Zhang, Decheng Suo, Peilong Wang, Kang Ma, Ruiguo Wang

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shulin WeiInstitute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Wei ZhangInstitute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Decheng SuoInstitute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0001-9463-0297
Peilong WangInstitute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Kang MaNational Institute of Metrology of China, Beijing 100029, China.ORCID 0000-0001-9316-1310
Ruiguo WangInstitute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

Funding

the China Agriculture Research System CARS-35the National Key Research and Development Programs of China 2023YFD1301504
6 · The paper itself

Abstract

A bovine milk reference material was produced containing amoxicillin with a target concentration at the maximum residue limit. For the evaluation and characterization of the reference material, an isotope dilution-liquid chromatography/tandem mass spectrometry method was developed and validated. This material was prepared by collecting milk samples from cows treated with an appropriate amoxicillin injection, followed by freeze-drying, dilution, and homogenization of the authentic samples. The amoxicillin reference material, prepared in accordance with ISO Guide 35, was homogeneous and stable. It was assigned a certified value of (4.10 ± 0.13) μg/kg with a relative standard deviation between 2.93 and 5.29%, which meets the maximum residue limit (MRL) requirement of 4.0 μg/kg established by the United States, the European Union, and China. This reference material can be used for method validation and provides internal quality control assurance for the detection of amoxicillin.

Indexed as

amoxicillinisotope dilution–liquid chromatography/tandem mass spectrometrylyophilized bovine milkreference material

Identifiers

PMID41745986
PMCPMC12945065

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.