Evidence map›Paper›PMID 41745841›Full record

ArticleToxics2026

Concentrations and Probabilistic Health Risks of Seven Metals in Face and Eye Cosmetics Across Seven Asian Countries.

Sohyeon Choi, Jae-Hyun Kim, Aram Lee, Yong-Jun Jeon, Won Kim, Inja Choi, Jeongim Park

Abstract read
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sohyeon ChoiDepartment of Environmental Health Sciences, Soonchunhyang University, Asan 31548, Republic of Korea.ORCID 0000-0001-7709-6037
Jae-Hyun KimDepartment of Environmental Health Sciences, Soonchunhyang University, Asan 31548, Republic of Korea.
Aram LeeDepartment of Environmental Health Sciences, Soonchunhyang University, Asan 31548, Republic of Korea.ORCID 0000-0002-5759-7245
Yong-Jun JeonDepartment of Environmental Health Sciences, Soonchunhyang University, Asan 31548, Republic of Korea.
Won KimWonjin Institute for Occupational and Environmental Health, Seoul 02221, Republic of Korea.ORCID 0000-0003-1808-6677
Inja ChoiWonjin Institute for Occupational and Environmental Health, Seoul 02221, Republic of Korea.ORCID 0000-0002-7847-392X
Jeongim ParkDepartment of Environmental Health Sciences, Soonchunhyang University, Asan 31548, Republic of Korea.

Funding

Beautiful foundationSoonchunhyang University
6 · The paper itself

Abstract

Despite global restrictions like the Minamata Convention, heavy metal contamination in cosmetics remains a critical public health concern, with limited cross-country comparative data on heavy metal concentrations in cosmetics across Asian markets. We measured Hg, Pb, As, Cd, Sb, Cr, and Ni contents in 189 cosmetic products purchased in 2022 in Bangladesh, India, Indonesia, Korea, Malaysia, the Philippines, and Vietnam. Samples were screened by handheld X-ray fluorescence; Hg was quantified by a direct mercury analyzer and As, Cd, Cr, Ni, Pb, and Sb were quantified by ICP-OES. Principal component analysis (PCA) was used to characterize metal co-occurrence patterns, and Monte Carlo simulation was applied to estimate dermal systemic exposure dose, hazard quotients (HQ), and lifetime cancer risk (LCR). Mercury in face creams exhibited extreme heterogeneity (range: ND-67,000 mg/kg), while eye cosmetics contained elevated Arsenic levels (median 4.13 mg/kg). PCA distinctively separated Hg (PC2) from geogenic metals (As/Cr/Ni on PC1), suggesting intentional adulteration. Probabilistic risk estimates indicated upper-tail non-cancer risk for Hg in facial creams (95th percentile HQ 6.32; P[HQ>1] = 24.4%). As produced the highest LCR estimates (facial cream 95th percentile 2.60 × 10

Indexed as

cosmetic safetyheavy metalsmercury adulterationprobabilistic risk assessmentsource apportionment

Identifiers

PMID41745841
PMCPMC12944837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.