ArticleTomography (Ann Arbor, Mich.)2026
Ultrashort Echo Time Double Echo Steady-State MRI for Quantitative Conductivity Mapping in the Knee: A Feasibility Study.
Article in Tomography (Ann Arbor, Mich.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesTissue conductivity reflects ionic composition (e.g., sodium), providing critical insights into various diseases. Ultrashort echo time quantitative conductivity mapping (UTE-QCM) offers a method to obtain this information, which is particularly effective for musculoskeletal (MSK) tissues with short T2 relaxation times. The aim of this study is to develop a UTE-QCM framework using ultrashort echo time double echo steady-state (UTE-DESS) and validate its feasibility in the knee.
methodsAn ultrashort echo time double echo steady-state (UTE-DESS) sequence was used to acquire S+ and S- images and estimate the transmit radiofrequency field (B1
resultsIn both phantom and in vivo experiments, the integral-based QCM demonstrated improved robustness to noise compared to parabolic fitting. In the sodium phantom, the estimated conductivity showed high linearity with sodium concentrations. In the in vivo knee, the generated conductivity maps successfully visualized both long and short T2 tissues.
conclusionsWe demonstrated the feasibility of UTE-QCM as a novel quantitative imaging tool targeting short T2 tissues in the MSK system. This technique may facilitate the diagnosis and prognosis of joint disorders.
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