Evidence map›Paper›PMID 41745671›Full record

ArticleSports (Basel, Switzerland)2026

Cardiovascular Functioning Features in Individuals with Connective Tissue Dysplasia Engaged in Sports for the Disabled.

Kamiliia Vinokurova, Anna Zakharova, Yulia Zinovieva, Arseniy Epifanov, Anna Galdobina, Ekaterina Sharkova, Felix Blyakhman

Abstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kamiliia VinokurovaInstitute of Physical Education, Sports and Youth Policy, Ural Federal University, Ekaterinburg 620002, Russia.ORCID 0000-0003-2967-2655
Anna ZakharovaInstitute of Physical Education, Sports and Youth Policy, Ural Federal University, Ekaterinburg 620002, Russia.
Yulia ZinovievaDepartment of Functional Diagnostics, Sverdlovsk Regional Hospital No. 2, Ekaterinburg 620000, Russia.
Arseniy EpifanovInstitute of Physical Education, Sports and Youth Policy, Ural Federal University, Ekaterinburg 620002, Russia.
Anna GaldobinaInstitute of Physical Education, Sports and Youth Policy, Ural Federal University, Ekaterinburg 620002, Russia.ORCID 0009-0004-4549-1285
Ekaterina SharkovaInstitute of Physical Education, Sports and Youth Policy, Ural Federal University, Ekaterinburg 620002, Russia.
Felix BlyakhmanInstitute of Physical Education, Sports and Youth Policy, Ural Federal University, Ekaterinburg 620002, Russia.ORCID 0000-0003-4434-2873

Funding

Ministry of Science and Higher Education of the Russian Federation 075-03-2023-006/13 (FEUZ-2023-0054)
6 · The paper itself

Abstract

objectivesConnective tissue dysplasia (CTD) is associated with disorders of collagen synthesis and is widely spread among the healthy population and people with disabilities. In the heart, primarily in the left ventricle (LV), CTD manifests itself as the formation of false tendons (LVFTs) to maintain close-to-normal LV pump function. This exploratory work is devoted to the search for general patterns of cardiac response to physical activity in athletes with disabilities, CTD, and LVFTs. The extent to which "the type of sports or the type of disability" determines the involvement of the heart's functional reserve is the main testable question of the proposed research.

methodsThe group under this study included 610 individuals with disabilities aged from 6 to 60 years with at least two transverse and/or oblique FTs per LV. Participants represented different sports disciplines (n = 10) and various forms of disabilities (n = 4). Cardiovascular indicators were obtained by means of standard TTE, impedance cardiography for hemodynamic monitoring in active orthotest, resting, and stress 12-lead ECG. Exercise testing of the athletes was performed with the use of appropriate methods of physical loading. In total, 141 parameters of cardiorespiratory function and exercise performance per participant were recorded. Statistical analysis of the dataset obtained across sports types or disability types was performed using one-way ANOVA or the Kruskal-Wallis test, depending on the assumptions of normality and homogeneity of variance.

resultsMost importantly, it was found that only maximum relative oxygen consumption (VO

conclusionsIn athletes with disabilities and CTD, sport specialization may involve the heart's functional reserve to a greater extent than the type of disability. To prescribe training loads for people with disabilities and CTD, individual cardiology screening with an emphasis on VO

Indexed as

adaptive sportscardiac adaptation to physical loadcardiorespiratory systemdisabilitiesheart functional reserveLV electromechanical functionLV false tendonsphysical exercises

Identifiers

PMID41745671
PMCPMC12944564

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