Evidence map›Paper›PMID 41745529›Full record

ArticleJournal of functional biomaterials2026

Osteogenic Potential of 3D Bioprinted Collagen Scaffolds Enriched with Bone Marrow Stromal Cells, BMP-2, and Hydroxyapatite in a Rabbit Calvarial Defect Model.

Diyana Vladova, Yordan Sbirkov, Elena Stoyanova, Tsvetan Chaprazov, Kiril K Dimitrov, Hristo Hristov, Dimitar Kostov, Petya Veleva, Daniela Stoeva, Victoria Sarafian

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diyana VladovaDepartment of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria.ORCID 0009-0006-1401-3429
Yordan SbirkovDepartment of Medical Biology, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-6554-3773
Elena StoyanovaDepartment of Molecular Immunology, Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, 1000 Sofia, Bulgaria.
Tsvetan ChaprazovDepartment of Veterinary Surgery, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria.
Kiril K DimitrovDepartment of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria.ORCID 0000-0003-2579-6968
Hristo HristovDepartment of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria.
Dimitar KostovDepartment of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria.
Petya VelevaDepartment of Agricultural Engineering, Faculty of Agriculture, Trakia University, 6000 Stara Zagora, Bulgaria.ORCID 0000-0001-7813-6387
Daniela StoevaDepartment of Biological Sciences, Faculty of Agriculture, Trakia University, 6000 Stara Zagora, Bulgaria.
Victoria SarafianDepartment of Medical Biology, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0003-1501-0175

Funding

This research was funded by Project № BG-RRP-2.004-0006, "Development of Research and Innovation at Trakia University in Service of Health and Sustainable Well-Being", implemented under the National Recovery and Resilience Plan of the Republic of Bulgaria Project № BG-RRP-2.004-0006
6 · The paper itself

Abstract

This study investigates the effect of three-dimensional (3D) bioprinted collagen (Col) scaffolds (2%

Indexed as

3D bioprinted scaffoldsbone marrow stromal cells (BMSCs)bone morphogenetic protein-2 (BMP-2)bone regenerationhydroxyapatiterabbit calvarial defect

Identifiers

PMID41745529
PMCPMC12941784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.