Evidence map›Paper›PMID 41745522›Full record

ArticleJournal of functional biomaterials2026

Electrospun Phage-Loaded Bilayer Nanofibrous Scaffolds for Wound Dressing Applications: A Comparative Study of Different Bacteriophages.

Siavash Aghili, Muhammed Awad, Md Hasib Adnan, George Bouras, Tran Thanh Tung, Sarah Vreugde, Dusan Losic

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siavash AghiliSchool of Chemical Engineering, Adelaide University, Adelaide, SA 5005, Australia.ORCID 0000-0001-8355-7848
Muhammed AwadDepartment of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research Woodville South, Adelaide University, Adelaide, SA 5011, Australia.ORCID 0000-0002-0402-6406
Md Hasib AdnanDepartment of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research Woodville South, Adelaide University, Adelaide, SA 5011, Australia.ORCID 0009-0008-1574-7138
George BourasDepartment of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research Woodville South, Adelaide University, Adelaide, SA 5011, Australia.
Tran Thanh TungSchool of Chemical Engineering, Adelaide University, Adelaide, SA 5005, Australia.ORCID 0000-0002-1535-5109
Sarah VreugdeDepartment of Surgery-Otolaryngology Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research Woodville South, Adelaide University, Adelaide, SA 5011, Australia.
Dusan LosicSchool of Chemical Engineering, Adelaide University, Adelaide, SA 5005, Australia.ORCID 0000-0002-1930-072X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is a growing global health threat, necessitating alternatives to conventional antibiotics. Bacteriophages, viruses that specifically target bacteria, represent a promising option, and phage-loaded electrospun fibers have recently gained attention as wound dressings for localized phage therapy. However, the influence of phage morphology and scaffold design has been largely overlooked. This study investigates how phage morphology and structure, in conjunction with scaffold design and processing conditions, may influence the biological performance of electrospun scaffolds. A bilayer scaffold was developed comprising a supportive polycaprolactone (PCL)/gelatin (70:30) layer and a polyvinyl alcohol (PVA) top layer loaded with bacteriophages. Two phage types, short-tailed podovirus APTC-SL.1 and long-tailed myovirus APTC-Efa.20, were incorporated into PVA fibers to evaluate their antibacterial activity against

Indexed as

antibacterial efficacyelectrospinningphagesphage therapywound dressingwound healing

Identifiers

PMID41745522
PMCPMC12941417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.