Evidence map›Paper›PMID 41745317›Full record

ArticleJournal of cardiovascular development and disease2026

Tnni3k Is Cardioprotective in Viral Myocarditis.

Kelsey Tjen, Ruolan Song, Baylee C Westbury, Lunndon A Lewis, Ge Tao, Kristine Y DeLeon-Pennell, Katelyn A Bruno, Henry M Sucov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelsey TjenDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0001-8033-813X
Ruolan SongDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.
Baylee C WestburyDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.
Lunndon A LewisDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.
Ge TaoDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0003-3724-487X
Kristine Y DeLeon-PennellDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-9647-6112
Katelyn A BrunoDivision of Cardiovascular Medicine, Department of Medicine, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0001-8980-6059
Henry M SucovDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-3792-3795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severity of viral myocarditis in humans and mice is variable between individuals. Numerous observations demonstrate the influence of host genetics on disease course, but few genes have actually been identified to have such properties. In past work, mouse strains that are sensitive or resistant to severe disease were used to map the viral myocarditis susceptibility locus

Indexed as

CVB3Tnni3kviral myocarditis

Identifiers

PMID41745317
PMCPMC12941999

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.