Evidence map›Paper›PMID 41745146›Full record

ArticleNanomaterials (Basel, Switzerland)2026

Nanobubble-Mediated Oxygen Delivery Mitigates Hypoxia-Induced ROS and HIF-1α Expression in UC-MSCs.

Sergio M Víafara-García, Gloria Torres, Carlos Chacón, Juan L Palma, Javier Rojas-Nunez, Esteban Landaeta, Juan Pablo Acevedo Cox

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sergio M Víafara-GarcíaCenter of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT), Santiago 7620086, Chile.ORCID 0000-0002-4208-1422
Gloria TorresCenter of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT), Santiago 7620086, Chile.
Carlos ChacónCenter of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT), Santiago 7620086, Chile.
Juan L PalmaResearch Center for Materials Engineering CIIMAT, Universidad Central de Chile, Santiago 8370178, Chile.ORCID 0000-0003-2068-174X
Javier Rojas-NunezCenter of Nanoscience and Nanotechnology (CEDENNA), Santiago 8340263, Chile.ORCID 0000-0002-2343-3533
Esteban LandaetaLaboratory of Atomic Force Microscopy (AFM), Department of Natural Sciences and Technology, Universidad de Aysén, Coyhaique 5951537, Chile.ORCID 0000-0002-1417-5181
Juan Pablo Acevedo CoxCenter of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT), Santiago 7620086, Chile.ORCID 0000-0002-7404-3762

Funding

Agencia Nacional de Investigación y Desarrollo (ANID) 21200641; 1201491Center of Interventional Medicine for Precision and Advanced Cellular Therapy (IMPACT) FB210024Fondequip Program 210088; 200182
6 · The paper itself

Abstract

Hypoxia and nutrient-deprived microenvironments pose significant challenges to the survival of transplanted human umbilical cord mesenchymal stem cells (UC-MSCs), necessitating the development of controllable oxygen delivery strategies. In this study, we engineered fluorosurfactant-coated oxygen nanobubbles (Tivida

Indexed as

fluorosurfactanthypoxiamesenchymal stem cellsnanobubblesoxygenationROS

Identifiers

PMID41745146
PMCPMC12942944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.