ReviewGels (Basel, Switzerland)2026
Research on Polysaccharide-Protein Composite Hydrogels for Gastrointestinal Targeted Delivery: A Review.
Review in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Design-Driven Gel-Based Delivery Systems for Bioactives in Sports Nutrition.Gels (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polysaccharide-protein composite hydrogels have demonstrated remarkable potential in targeted gastrointestinal delivery owing to their excellent biocompatibility, adjustable physicochemical characteristics, and intelligent responsiveness. This review provides a comprehensive overview of the underlying mechanisms and diverse applications of these composite hydrogels in gastrointestinal targeted delivery, with a particular emphasis on their stimuli-responsive release behaviors triggered by internal and external factors such as pH, enzymes, magnetic fields. Special attention is also given to their advantages in protecting sensitive bioactive ingredients, including curcumin, EGCG, probiotics. Furthermore, this review highlights their capabilities in achieving high encapsulation efficiency, smart controlled release and targeted delivery, while also presenting current challenges associated with material stability, targeting precision, large-scale production, and clinical translation. Finally, future perspectives are discussed, focusing on the development of multi-response system design, innovative biomaterials, advanced manufacturing technology applications, and AI-assisted optimization. These directions aim to provide theoretical foundations and technical strategies for advanced research and practical applications of polysaccharide-protein composite hydrogels in a targeted gastrointestinal delivery system. Overall, this review underscores the significant promise of polysaccharide-protein composite hydrogels as intelligent gastrointestinal delivery platforms and provides a systematic reference for their rational design and future translational development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.