ArticleGels (Basel, Switzerland)2026
Magnetic-Graphene-Oxide-Incorporated Alginate Hydrogel Beads as a Potential Controlled Drug Delivery System.
Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The trial behind it
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Who cites it
2 citing papers in PubMed.
- Synthesis, characterization and application of poly(ε-caprolactone-co-2-ethyl-2-oxazoline) as a carrier for procaine: microsphere formulation, drug release, and antimicrobial activity.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Design and Evaluation of Alginate-Based Hydrogels for Controlled Release of Cationic and Anionic Model Compounds.Gels (Basel, Switzerland) · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to synthesize alginate hydrogel beads using ionotropic gelation containing pH-sensitive magnetic reduced graphene oxide (MGO). MGO was prepared using a hydrothermal method and surrounded by alginate beads. FTIR, XRD, FESEM, TEM, VSM and TGA showed that the synthesized beads have a quasi-spherical structure, exhibit superparamagnetic behavior, and are thermally stable up to 350 °C. The model drug, quercetin, was loaded into these particles with an efficiency of 25.8%. These particles showed a pH-dependent release. HFF-2 and Caco-2 cells were used to investigate cytotoxicity. At a concentration of 140 μg/mL, more than 80% viability was observed in HFF-2 cells and anticancer effects were observed on Caco-2 cells with a decrease in viability of less than 50% at a concentration of 200 μg/mL. The obtained cell culture results indicate that the hydrogel beads are biocompatible and act as a drug delivery system.
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