Evidence map›Paper›PMID 41745023›Full record

ReviewGels (Basel, Switzerland)2026

3D Printing with Tragacanth-Gum-Based Bioinks: A New Frontier in Bioprinting Materials.

Shivani Dogra, Bhupendra Koul, Ananta Prasad Arukha, Muhammad Fazle Rabbee

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shivani DograDepartment of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, India.ORCID 0000-0002-0656-2560
Bhupendra KoulDepartment of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, India.ORCID 0000-0002-8409-3624
Ananta Prasad ArukhaDepartment of Infectious Disease and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32110, USA.ORCID 0000-0003-0382-6054
Muhammad Fazle RabbeeDepartment of Biotechnology, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0003-2497-5219

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extrusion-based bioprinting is widely used for fabricating cell-laden constructs; however, its success is highly dependent on the rheological and biological performance of the bioink. Natural polysaccharide gums have emerged as promising bioink components due to their biocompatibility and tunable properties. Among them, tragacanth gum (TG), a complex anionic heteropolysaccharide composed of tragacanthin and bassorin fractions, has gained increasing attention for extrusion bioprinting applications. TG exhibits pronounced shear-thinning behavior, high water uptake, and spontaneous gel-forming ability, which collectively enhance the printability, shape fidelity, and structural stability of bioinks. This review critically summarizes recent advances in TG-based hydrogels and bioinks, with emphasis on their molecular characteristics, rheological and physicochemical properties, and biological performance in extrusion bioprinting systems. The role of TG as a functional component in composite bioinks, particularly in improving mechanical integrity, extrusion consistency, and cytocompatibility, is discussed. Finally, current challenges and future research directions are highlighted to support the development and clinical translation of TG-based bioinks for tissue engineering applications.

Indexed as

biocompatibilitybioinksextrusion bioprintinghydrogel scaffoldstissue engineeringtragacanth gum

Identifiers

PMID41745023
PMCPMC12939937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.