Intrinsically Thermoresponsive Hydrogels from Molecularly Engineered Chitosan.

Xiaohan Zha, Chen Wang, Zhuoying Meng, Yiwen Ye, Hui Sun, Chengyu Tan, Ye Tian

Abstract read

In one paragraph

Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaohan ZhaKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.ORCID 0009-0008-3778-2241

Chen WangKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.

Zhuoying MengKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.

Yiwen YeKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.

Hui SunKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.

Chengyu TanKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.

Ye TianKey Laboratory of Environment Controlled Aquaculture, Dalian Ocean University, Ministry of Education, Dalian 116023, China.ORCID 0000-0002-9750-7777

Funding

Dalian, Science and Technology Innovation Fund 2024JJ13GX047Liaoning Provincial Natural Science Foundation Support Program Project 2025-MSLH-126National Natural Science Foundation of China 22278062, 31901775

6 · The paper itself

Abstract

Thermoresponsive chitosan hydrogels hold significant promise for advancing biomedical technologies, yet their frequent reliance on petroleum-based polymers raises biosafety and environmental concerns. The present study utilized a molecular functionalization strategy to transform chitosan into thermoresponsive alkylated chitosan (ICS). The ICS was subsequently covalently crosslinked to construct a fully degradable, all-chitosan thermoresponsive hydrogel (TR-ICS

Indexed as

alkylated chitosandegradabilityhydrogelsthermoresponsivetunable VPTT

Identifiers

PMID41744991

DOI10.3390/gels12020119

PMCPMC12940993

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.