Evidence map›Paper›PMID 41744904›Full record

ArticlemSphere2026

The IrlS2-IrlR2 two-component system is a global regulator of biofilm formation, stress adaptation, and virulence in

Fang Chen, Jian Luo, Yingjuan Wang, Shen Tian, Xun Kang, Nan Zhang, Wan Zheng, Wenting Li, Qianfeng Xia, Dai Kuang

Abstract read
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fang Chen *NHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.ORCID 0009-0003-2873-7602
Jian Luo *NHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.
Yingjuan Wang *NHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.
Shen TianNHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.
Xun KangNHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.
Nan ZhangNHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.
Wan ZhengNHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.
Wenting LiDepartment of Infectious and Tropical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.ORCID 0000-0001-7734-4838
Qianfeng XiaNHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.ORCID 0000-0002-5737-4842
Dai KuangNHC Key Laboratory of Tropical Disease Control, School of Life Sciences and Medical Technology, Hainan Medical University, Haikou, China.ORCID 0009-0003-1228-555X

Funding

Hainan Medical University XSTS2025159Hainan Provincial Department of Science and Technology 825QN334Hainan Provincial Department of Science and Technology 825RC764National Natural Science Foundation of China U24A20747
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

Adaptation, PhysiologicalBacterial ProteinsBiofilmsBurkholderia pseudomalleiStress, PhysiologicalA549 CellsAnimalsGene Expression Regulation, BacterialHumansMelioidosisMothsOxidative StressSignal TransductionVirulenceBacterial Proteinsbiofilm formationBurkholderia pseudomalleistress adaptationtwo-component systemsvirulence regulation

Identifiers

PMID41744904
PMCPMC13037405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.