Evidence map›Paper›PMID 41744884›Full record

GuidelineCurrent oncology (Toronto, Ont.)2026

Romanian Consensus Statement for Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer (HR+/HER2- mBC) and Triple-Negative Metastatic Breast Cancer (mTNBC).

Mircea Dragoș Median, Nicoleta Zenovia Antone, Simona Volovăț, Laura Mazilu, Șerban Mircea Negru, Răzvan Ovidiu Curcă, Amedeia Niță, Raluca Ileana Pătru, Andrei Ungureanu, Vlad Lupu and 1 more

Abstract readGuideline
In one paragraph

Guideline in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mircea Dragoș MedianFilantropia Clinical Hospital, 011132 Bucharest, Romania.ORCID 0000-0001-5842-1850
Nicoleta Zenovia AntoneBreast Tumors Center, Institute of Oncology "Prof. Dr. Ion Chiricuta", 400015 Cluj-Napoca, Romania.ORCID 0000-0002-7497-5578
Simona VolovățRegional Institute of Oncology, 700483 Iași, Romania.
Laura MaziluOvidius Clinical Hospital, 905900 Constanța, Romania.ORCID 0000-0001-6195-4500
Șerban Mircea NegruDepartment of Oncology, Faculty of Medicine, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Răzvan Ovidiu CurcăElysee Hospital, 510040 Alba Iulia, Romania.
Amedeia NițăMunicipal Hospital, 100337 Ploiești, Romania.
Raluca Ileana PătruColțea Clinical Hospital, 030167 Bucharest, Romania.
Andrei UngureanuAmethyst Radiotherapy Center, 407280 Cluj-Napoca, Romania.
Vlad LupuDepartment of Oncology, Faculty of Medicine, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0001-6840-9310
Cristina Marinela OpreanDepartment of Oncology, ONCOHELP Hospital, 300239 Timisoara, Romania.ORCID 0000-0001-5000-5422

Funding

Gilead Sciences (GSR) SRL Romania N/A
6 · The paper itself

Abstract

Breast cancer (BC) is the most common malignant disease in women in Romania, with incidence and mortality rates among the highest in Europe. This consensus statement aims to ensure equitable access to care for human epidermal growth factor receptor 2-negative metastatic BC (HR+/HER2- mBC) and triple-negative mBC (mTNBC) in Romania. Between December 2024 and June 2025, a scientific board of 11 oncologists, in collaboration with the Romanian National Society for Medical Oncology (SNOMR), developed national recommendations based on ESMO/NCCN/ABC guidelines, clinical expertise, and local conditions. A modified Delphi survey was conducted among medical oncologists to evaluate acceptance of recommendations with greatest clinical impact. Key recommendations included: mandatory biopsy at metastasis with ER/PgR/HER2 retesting, HER2-low assessment, and molecular profiling (

Indexed as

consensus statementDelphi surveyguidelineshormone receptor-positive and human epidermal growth factor receptor 2-negative metastatic breast cancer (HR+/HER2– mBC)Romaniatriple-negative metastatic breast cancer (mTNBC)

Identifiers

PMID41744884
PMCPMC12940007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.