Evidence map›Paper›PMID 41744784›Full record

ArticleCells2026

TRPV4 Deficiency Shifts Mitochondrial Dynamics Toward a Fragmented Morphology in Primary Microglia.

Elena-Andreea Burlacu, Robin Schellingen, Amanda Moya-Gómez, Sanne G S Verberk, Nathan Stas, Sofie Kessels, Yeranddy A Alpizar, Jean-Michel Rigo, Annelies Bronckaers, Jerome J A Hendriks and 2 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elena-Andreea BurlacuBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0003-4930-2723
Robin SchellingenBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0009-0007-7130-350X
Amanda Moya-GómezBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0002-0766-6249
Sanne G S VerberkBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0003-4509-4824
Nathan StasBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.
Sofie KesselsBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0002-0070-7482
Yeranddy A AlpizarBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0003-1959-5393
Jean-Michel RigoBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0002-0031-526X
Annelies BronckaersBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.
Jerome J A HendriksBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0002-7717-8582
Christel FaesData Science Institute (DSI), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0002-1878-9869
Bert BrôneBiomedical Research Institute (BIOMED), Hasselt University (UHasselt), 3590 Diepenbeek, Belgium.ORCID 0000-0002-4851-9480

Funding

Hasselt University BOF21GP05
6 · The paper itself

Abstract

Microglia perform surveillance and phagocytosis to maintain the homeostasis of the central nervous system (CNS). These processes are energetically demanding, and given the critical roles of mitochondria in providing ATP, the characteristics of the mitochondrial network can modulate microglial behavior. Although the Ca

Indexed as

microgliamitochondriaTRPV4

Identifiers

PMID41744784
PMCPMC12939844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.