Evidence map›Paper›PMID 41744727›Full record

ArticleBiosensors2026

Development of Advanced Nanobiosensors and a Portable Monitoring System for Pesticide Detection at the Point of Need.

Evangelos Skotadis, Menelaos Tsigkourakos, Emmanouil Anthoulakis, Myrto-Kyriaki Filippidou, Sotirios Ntouskas, Maria Kainourgiaki, Charalampos Tsioustas, Chrysi Panagopoulou, Stergios Dimou-Sakellariou, Nikos Kalatzis and 6 more

Abstract read
In one paragraph

Article in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Evangelos SkotadisDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.ORCID 0000-0002-7572-4375
Menelaos TsigkourakosDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.
Emmanouil AnthoulakisDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.ORCID 0009-0002-0136-4757
Myrto-Kyriaki FilippidouInstitute of Nanoscience and Nanotechnology, NCSR "Demokritos", 15341 Aghia Paraskevi, Greece.ORCID 0000-0001-6972-745X
Sotirios NtouskasInstitute of Nanoscience and Nanotechnology, NCSR "Demokritos", 15341 Aghia Paraskevi, Greece.
Maria KainourgiakiDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.
Charalampos TsioustasDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.ORCID 0000-0002-0410-0573
Chrysi PanagopoulouDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.
Stergios Dimou-SakellariouNEUROPUBLIC S.A., 6 Methonis Str., 18545 Piraeus, Greece.
Nikos KalatzisNEUROPUBLIC S.A., 6 Methonis Str., 18545 Piraeus, Greece.
Eleftherios A PetrakisNEUROPUBLIC S.A., 6 Methonis Str., 18545 Piraeus, Greece.
Nikolaos AlexisDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.ORCID 0000-0002-2949-1486
George TsekenisApplied Biophysics and Surface Science Group, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.ORCID 0000-0002-5780-1074
Angeliki TserepiInstitute of Nanoscience and Nanotechnology, NCSR "Demokritos", 15341 Aghia Paraskevi, Greece.ORCID 0000-0002-5426-1383
Stavros ChatzandroulisInstitute of Nanoscience and Nanotechnology, NCSR "Demokritos", 15341 Aghia Paraskevi, Greece.
Dimitris TsoukalasDepartment of Applied Physics, National Technical University of Athens, 15780 Zografou, Greece.ORCID 0000-0001-5189-3396

Funding

European Union and Greek national funds ATTP4-0325463
6 · The paper itself

Abstract

This work presents the development of an automated and portable monitoring system for the point-of-need detection of tebuconazole and lambda-cyhalothrin. The system features nanoparticle/aptamer-modified electrochemical sensors that are integrated into a microfluidic chip based on polydimethylsiloxane (PDMS). More specifically, rapid and selective detection of both pesticides is achieved using target-specific aptamers immobilized on two-dimensional platinum nanoparticle films that serve as expanded nano-gapped electrodes to enhance sensor sensitivity. The effect of the device substrate (i.e., silicon versus flexible substrates) and measurement setup on biosensing performance has also been investigated. The final monitoring system is characterized by high sensitivity and selectivity in the cases of both target analytes and substrates. Τhe system features a limit of detection of 9.85 pM for tebuconazole, which is one of the lowest reported values in the literature; for lambda-cyhalothrin, it is worth noting that the results reported herein represent one of the few studies on an electrochemical aptamer-based sensor for this analyte, featuring a limit of detection of 48.5 pM. The system is also capable of selectively detecting both targets for complex cross-reactive sample matrices consisting of commercially available pesticides. Moreover, its use could be expanded to detect additional pollutants by functionalizing the biosensor surface with appropriate aptamers.

Indexed as

aptamersaptasensorelectrochemicallambda-cyhalothrinmicrofluidic chipnanoparticlespoint of carepyrethroidtebuconazoletriazole

Identifiers

PMID41744727
PMCPMC12938364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.