Evidence map›Paper›PMID 41744617›Full record

ArticleBiology2026

CHMP7/ESCRT-III Is Localized at the Nuclear Envelope of Cortical Neurons and Required for Expression of Activity-Regulated Genes.

Paola Chietera, Heidrun Berger, Nico Wahl, Mujahid Ali, Galina Apostolova

Abstract read
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paola ChieteraInstitute for Neuroscience, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-9247-9949
Heidrun BergerInstitute for Neuroscience, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Nico WahlInstitute for Neuroscience, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-6220-7873
Mujahid AliInstitute for Neuroscience, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-3583-493X
Galina ApostolovaInstitute for Neuroscience, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-2682-4385

Funding

FWF Austrian Science Fund 10.55776/COE16FWF Austrian Science Fund FWF-P33027-BTyrolean Research Fund F.47940/6-2023
6 · The paper itself

Abstract

The epigenome and nuclear architectural mechanisms that regulate neuronal activity-induced transcriptional responses in cortical neurons remain incompletely understood. Previously, we have shown that the chromatin organizer SATB2 and the inner nuclear membrane protein LEMD2 form a chromatin tether at the nuclear lamina, and that activity-induced transcription is impaired in both

Indexed as

cortical neuronESCRT-IIIgene expressionneuronal activitynuclear envelope

Identifiers

PMID41744617
PMCPMC12937594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.