Evidence map›Paper›PMID 41744605›Full record

ArticleBiology2026

Regulatory T Cells and IFNγ in Mercury-Induced Autoimmunity: Insights from Adoptive Transfer in B10.S Mice.

Rebecka Salwén, Mehdi Amirhosseini, Said Havarinasab

Erratum issuedAbstract read
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In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Rebecka SalwénDivision of Inflammation and Infection (II), Department of Biomedical and Clinical Sciences, Linköping University, 581 83 Linkoping, Sweden.ORCID 0009-0009-3017-3790
Mehdi AmirhosseiniDivision of Inflammation and Infection (II), Department of Biomedical and Clinical Sciences, Linköping University, 581 83 Linkoping, Sweden.
Said HavarinasabDivision of Clinical Chemistry and Pharmacology (KKF), Department of Biomedical and Clinical Sciences, Linköping University, 581 83 Linkoping, Sweden.ORCID 0000-0003-0379-630X

Funding

Ingrid Asp foundation, and Linkoping University LiU 2017-02122
6 · The paper itself

Abstract

Autoimmune diseases result from a breakdown of immune tolerance influenced by genetic and environmental factors. Regulatory T cells (Tregs) maintain immune homeostasis, while interferon-γ (IFNγ) has context-dependent proinflammatory and regulatory roles. In B10.S mice, mercury-induced autoimmunity (HgIA) emerges within approximately 4 weeks of Hg exposure and is marked by antinucleolar antibody (ANoA) production, polyclonal B-cell activation, and deposition of immune complexes in the kidney. We investigated whether Tregs attenuate HgIA and evaluated IFNγ's role in this regulation. Female WT and IFNγ

Indexed as

antinucleolar antibodies (ANoA)autoimmunityB10.S miceinterferon-gamma (IFNγ)mercury-induced autoimmunity (HgIA)regulatory T cells

Identifiers

PMID41744605
PMCPMC12938244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.