Evidence map›Paper›PMID 41744592›Full record

ReviewBiomimetics (Basel, Switzerland)2026

Current Applications and Future Perspectives of Artificial Intelligence in Face-Driven Orthodontics: A Scoping Review.

Barbora Heribanová, Katarína Janáková, Juraj Tomášik, Daniela Tichá, Štefan Harsányi, Andrej Thurzo

Abstract readReview
In one paragraph

Review in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbora HeribanováDepartment of Orthodontics, Regenerative and Forensic Dentistry, Faculty of Medicine and KORFS, Comenius University in Bratislava, Dvorakovo Nabrezie 4, 81102 Bratislava, Slovakia.ORCID 0009-0002-0640-2206
Katarína JanákováDepartment of Orthodontics, Regenerative and Forensic Dentistry, Faculty of Medicine and KORFS, Comenius University in Bratislava, Dvorakovo Nabrezie 4, 81102 Bratislava, Slovakia.ORCID 0009-0005-6472-2170
Juraj TomášikDepartment of Orthodontics, Regenerative and Forensic Dentistry, Faculty of Medicine and KORFS, Comenius University in Bratislava, Dvorakovo Nabrezie 4, 81102 Bratislava, Slovakia.ORCID 0009-0000-1096-4485
Daniela TicháDepartment of Orthodontics, Regenerative and Forensic Dentistry, Faculty of Medicine and KORFS, Comenius University in Bratislava, Dvorakovo Nabrezie 4, 81102 Bratislava, Slovakia.ORCID 0009-0004-1082-1248
Štefan HarsányiInstitute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University in Bratislava, Sasinkova 4, 81108 Bratislava, Slovakia.ORCID 0000-0002-7889-4898
Andrej ThurzoDepartment of Orthodontics, Regenerative and Forensic Dentistry, Faculty of Medicine and KORFS, Comenius University in Bratislava, Dvorakovo Nabrezie 4, 81102 Bratislava, Slovakia.ORCID 0000-0002-7810-5721

Funding

Ministry of Education, Research, Development and Youth of the Slovak Republic NFP401101B343 - Simulation and Training Centre for General and Dental Medicine Faculty of Medicine, Comenius University in BratislavaOffice of the Deputy Prime Minister of Slovakia Industrial Research and Experimental Development Projects in the Field of Biotechnologies PK 1/2025 ScaniFy
6 · The paper itself

Abstract

Artificial Intelligence (AI) has introduced transformative possibilities in orthodontics by enhancing diagnostic precision, treatment planning, and aesthetic outcomes. In face-driven orthodontics, treatment objectives extend beyond achieving proper occlusion to optimizing facial balance and harmony. With the growing patient demand for aesthetic improvements, AI technologies enable clinicians to integrate facial analysis and dynamic soft-tissue evaluation into personalized treatment approaches. Research in this scoping review analyzed current applications of AI in face-driven orthodontics, focusing on diagnosis, soft-tissue assessment, and individualized treatment planning. A comprehensive search was conducted in PubMed and Scopus for studies published between 2021 and 2025. The review followed the PRISMA-ScR guidelines. Of 54 initially identified studies, 24 met the inclusion criteria after title, abstract, and full-text screening. Extracted data were organized according to the main application areas of AI in face-driven orthodontics. Most studies focused on AI-assisted facial analysis, 3D reconstruction, and treatment simulation. Deep learning models demonstrated high performance in soft-tissue prediction, aesthetic evaluation, and diagnostic accuracy. However, heterogeneity in datasets, a lack of standardized validation protocols, limited external validation across included studies and limited clinical applicability were identified as key limitations. AI-based facial analysis supports a shift toward individualized, aesthetics-oriented orthodontic planning. Although current evidence highlights its potential for improving diagnostic precision and treatment outcomes, further validation through large-scale clinical studies is essential for broader implementation in everyday practice.

Indexed as

aestheticsAIdeep learningdiagnosisindividualized treatment planningmachine learningsoft tissue analysis

Identifiers

PMID41744592
PMCPMC12937609

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.