Evidence map›Paper›PMID 41744493›Full record

ArticleAndrology2026

Nut Consumption and Sperm Quality in Healthy Men: Results From the Led-Fertyl Study.

Estefanía Dávila-Córdova, Nancy Babio, Cristina Valle-Hita, María Fernández de la Puente, Alfonso Beltran-Arasa, Miguel Cebrián-Puig, Violeta Fambuena-Perez, Iván García-Serrano, Michelle M Murphy, Jordi Salas-Salvadó and 1 more

Abstract read
In one paragraph

Article in Andrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Estefanía Dávila-CórdovaDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.ORCID https://orcid.org/0000-0003-1153-9397
Nancy BabioInstitut D'investigació Sanitària Pere Virgili (IISPV), Reus, Spain.ORCID https://orcid.org/0000-0003-3527-5277
Cristina Valle-HitaDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.ORCID https://orcid.org/0000-0001-5423-7466
María Fernández de la PuenteDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.ORCID https://orcid.org/0000-0002-7164-3420
Alfonso Beltran-ArasaDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.
Miguel Cebrián-PuigDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.
Violeta Fambuena-PerezDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.
Iván García-SerranoDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.
Michelle M MurphyInstitut D'investigació Sanitària Pere Virgili (IISPV), Reus, Spain.ORCID https://orcid.org/0000-0002-6304-6204
Jordi Salas-SalvadóDepartament de Bioquímica i Biotecnologia, Unitat de Nutrició Humana, Alimentació, Nutrició, Desenvolupament i Salut Mental ANUT-DSM, Universitat Rovira i Virgili, Reus, Spain.ORCID https://orcid.org/0000-0003-2700-7459
Albert Salas-HuetosInstitut D'investigació Sanitària Pere Virgili (IISPV), Reus, Spain.ORCID https://orcid.org/0000-0001-5914-6862

Funding

Carlos III Health Institute (ISCIII), Fondo de Investigación para la Salud (FIS); European Union ERDF/ESF PI21/01447Carlos III Health Institute, Spanish Ministry of Health, Contrato Pre-doctoral de Formación en Investigación en Salud (PFISFI22/00018)Diputació de Tarragona 2021/11-No.Exp. 8004330008-2021-0022642Institució Catalana de Recerca i Estudis Avançats (ICREA) Academia Program
6 · The paper itself

Abstract

backgroundNuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.

objectiveThe study aimed to evaluate the association between nut consumption and sperm quality parameters in healthy men of reproductive age. MATERIALS AND

methodsA cross-sectional analysis was conducted using the data from 222 young men enrolled in the Led-Fertyl study. Nut consumption was categorized as < 3, ≥ 3 to < 7, and ≥ 7 servings/week (1 serving = 30 g). The main outcomes were sperm quality parameters (sperm count, concentration, vitality, motility, and normal morphology). Multivariate linear and logistic regression models were fitted to analyze associations.

resultsTotal sperm count (β = 3.38; 95%CI: 1.59, 5.16) and concentration (β = 1.17; 95%CI: 0.15, 2.19) were higher among participants in the highest category of nut consumption (≥7 servings/week) compared to those in the lowest (< 3 servings/week). A similar association was observed when modeling nut consumption as continuous; each additional serving per day was associated with higher total sperm count and concentration (β = 2.38; 95%CI: 1.03, 3.72 and β = 0.83; 95%CI: 0.06, 1.59, respectively). A theoretical substitution of 1 serving/day of nuts with 1 serving/day of potato chips or pastries was associated with lower total sperm count and concentration. Furthermore, compared to participants in the lowest category of nut consumption, those in the highest were 75% less likely to have abnormal sperm motility (OR: 0.25; 95%CI: 0.07, 0.95) and 69% less likely to have seminogram abnormalities (OR: 0.31; 95%CI: 0.14, 0.68).

conclusionsOur findings suggest that regular nut consumption is associated with higher total sperm count and concentration in young, healthy men of reproductive age.

Indexed as

DietNutsSemen AnalysisSpermatozoaAdultCross-Sectional StudiesHumansMaleSperm CountSperm MotilityYoung Adultmale fertilityMediterranean dietnutssperm qualityunsaturated fatty acids

Identifiers

PMID41744493
PMCPMC13592052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.