ArticleCirculation. Arrhythmia and electrophysiology2026
Impact of Catheter Configuration on the Mapping of Atrial Fibrillation.
Article in Circulation. Arrhythmia and electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Catheter configuration for mapping micro-anatomic reentries sustaining atrial fibrillation: A simulation study.PLoS computational biology · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundMapping of heart rhythms is influenced by the size and configuration of the mapping electrodes. Whether a recorded electrogram represents near (local) or remote activity influences diagnosis and treatment, yet is affected by mapping characteristics that are often undefined.
methodsWe developed biophysical computational models to predict interactions between the recording tool and cardiac tissue in coherent and disorganized rhythms, which we validated in clinical recordings.
resultsBiophysical computational models demonstrated the ability to quantify and visualize the recording antennae for different electrode configurations. Our results show that unipolar electrograms reflected a recording antenna within 3-dimensional ellipsoids of radius 8 mm across-tissue and 2.7 mm transmurally. Bipolar electrogram antennae align with propagation direction in ellipsoids of long axis radius 1.7, 5.7, and 8.3 mm for 2, 5, and 10 mm spacing, respectively, and often extend beyond the physical extent of electrodes. Notably, omnipolar electrograms, constructed from orthogonal bipoles in a triangular configuration, retained some directional preferences of bipolar electrograms, with a complex relationship between electrode orientation and wave direction. When tested clinically on high-resolution, narrow field (grid) catheters and moderate-to-low resolution, global (basket) catheters, antennae varied more with electrode type (correlation coefficient of 0.43 unipolar, 0.05 bipolar, and 0.26 omnipolar;
conclusionsThis novel computational-clinical system approach enabled us to systematically compare electrode configurations. This work may help interpret signals in complex biological rhythms, such as atrial fibrillation, and may influence the design of novel catheter configurations and signal processing approaches to identify local tissue signals.
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