Evidence map›Paper›PMID 41743860›Full record

ArticleJournal of molecular liquids2025

Comparative analysis of drug deposition patterns among three commercial nasal spray brands: A computational and experimental study.

Guiliang Liu, Mohammad Hossein Doranehgard, Xuan Ruan, Bingkai Chen, Brent Senior, Adam Kimple, Rui Ni, Zheng Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular liquids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guiliang LiuDepartment of Mechatronics Engineering, Morgan State University, Baltimore, MD 21251, USA.
Mohammad Hossein DoranehgardDepartment of Mechatronics Engineering, Morgan State University, Baltimore, MD 21251, USA.
Xuan RuanDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Bingkai ChenDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Brent SeniorDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill, USA.
Adam KimpleDepartment of Otolaryngology/Head & Neck Surgery, University of North Carolina at Chapel Hill, USA.
Rui NiDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Zheng LiDepartment of Mechatronics Engineering, Morgan State University, Baltimore, MD 21251, USA.

Funding

Subject specific modeling of drug absorption in nasal cavityR16GM153629 · NIGMS · MORGAN STATE UNIVERSITY · PI Zheng li · 2024 to 2026
$470k
NIGMS NIH HHS R16 GM153629
6 · The paper itself

Abstract

This study investigates drug deposition patterns in nasal drug delivery by combining experimental measurements with computational fluid dynamics simulations. We analyzed three, over the counter, mometasone nasal spray devices, experimentally characterizing particle diameter (dp), spray velocity (up), and spray angle

Indexed as

Computational fluid dynamicsDrug deposition efficiencyLine of Sight (LOS) methodNasal drug deliverySpray particle parameters

Identifiers

PMID41743860
PMCPMC12931824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.