Evidence map›Paper›PMID 41743837›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Evaluation of the hemostatic efficacy and safety of an absorbable hemostatic powder based on a porcine intracranial hemorrhage model.

Jiali Shi, Yun Zhou, Yang Fu, Jin Wang

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiali ShiHangzhou Singclean Medical Products Co., Ltd., Hangzhou, China.
Yun ZhouHangzhou Singclean Medical Products Co., Ltd., Hangzhou, China.
Yang FuHangzhou Singclean Medical Products Co., Ltd., Hangzhou, China.
Jin WangHangzhou Singclean Medical Products Co., Ltd., Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This work aimed to evaluate the hemostatic efficacy and safety of an absorbable hemostatic powder in intracranial hemorrhage of porcine model. Method: Absorbable hemostatic powder was prepared from potato starch via mulsification and cross-linking technology, followed by structural characterization. An intracranial and extracranial injury hemorrhage in Bama miniature pigs' model was established to evaluate the safety and effectiveness of the absorbable hemostatic powder. The biophysical characteristics of the absorbable hemostatic powder were compared with the control group and marketed product. Results: Absorbable hemostatic powder is a multi-microsphere with a spatial reticular microstructure with a porosity of 61.77%. Its water absorption rate reached over 1,200%. Animal research results showed that the hemostasis time and bleeding volume of the absorbable hemostatic powder were 73.50 ± 29.08 s and 3.90 ± 2.09 g, respectively. Compared with the model control group, both were significantly reduced ( Discussion: The conclusion indicated that the absorbable hemostatic powder was safe and effective in neurosurgical applications. Its porous structure design combines the advantages of rapid hemostasis and biocompatibility, providing a new idea for the development of clinical hemostatic materials.

Indexed as

absorbable hemostatic powdereffectivenessneurosurgeryporcine intracranial hemorrhage modelsafety

Identifiers

PMID41743837
PMCPMC12929469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.