ArticleEnvironment & health (Washington, D.C.)2026
Impact of Ozone Exposure on Oral Microbiome: A Controlled, Randomized, Crossover Trial.
Article in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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16 authors.
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Abstract
Environmental ozone pollution may adversely impact human health, while dysbiosis is implicated in various health outcomes. However, the effects of ozone exposure on the human microbiome remain unclear. This study conducted a controlled, randomized, crossover ozone exposure trial with 29 participants exposed to filtered air and ozone. Oral microbiome samples were collected for 16S rRNA sequencing. A mixed-effects model was used to analyze the impact of ozone exposure on the diversity and composition of the oral microbiome, as well as their association with lung functions. The results showed that the ozone concentration remained stable at 5 ± 5.1 parts per billion (ppb) under filtered air and 282.2 ± 44 ppb during ozone exposure. Acute ozone exposure significantly impaired lung function and reduced oral microbiome diversity, with forced vital capacity (FVC) decreasing by 0.41 L, expiratory volume in one second (FEV
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