Evidence map›Paper›PMID 41743699›Full record

ArticleEngineering in life sciences2026

Optimized Bioconversion of Naringenin to Hesperetin in

Maik Wildhagen, Nina Malke, Qimin Wang, Xiaoying Zhuang, Sascha Beutel

Abstract read
In one paragraph

Article in Engineering in life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maik WildhagenInstitute of Technical Chemistry Leibniz University Hannover Hannover Germany.
Nina MalkeInstitute of Technical Chemistry Leibniz University Hannover Hannover Germany.
Qimin WangInstitute of Photonics Leibniz University Hannover Hannover Germany.
Xiaoying ZhuangInstitute of Photonics Leibniz University Hannover Hannover Germany.
Sascha BeutelInstitute of Technical Chemistry Leibniz University Hannover Hannover Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hesperetin is a bioactive flavonoid with potential applications in pharmaceuticals and nutraceuticals, yet its low natural abundance limits commercial use. In this study, a two-step whole-cell bioconversion process was developed for the microbial production of hesperetin from naringenin in

Indexed as

halide methyltransferase hesperetinHpaBCO‐methyltransferasewhole‐cell biocatalysis

Identifiers

PMID41743699
PMCPMC12930279

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.