Evidence map›Paper›PMID 41743645›Full record

ArticleFrontiers in physiology2026

Navigating preanalytical challenges: a real-world study on single-tube pneumatic tube systems.

Lisha Li, Xiaofei Zhang, Nannan Xu, Miaoli Shao, Binxuan Chen, Feng Wu, Qi Zhao, Wensheng Wang, Jianxin Yan, Zhiheng Wang and 1 more

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Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lisha Li *Department of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Xiaofei Zhang *College of Mechanical Engineering, Zhejiang University of Technology, Hangzhou, China.
Nannan XuDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Miaoli ShaoDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Binxuan ChenDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Feng WuDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Qi ZhaoDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Wensheng WangDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Jianxin YanDepartment of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.
Zhiheng Wang *College of Mechanical Engineering, Zhejiang University of Technology, Hangzhou, China.
Renfang Zhou *Department of Clinical Laboratory, The First People's Hospital of Wenling, Affiliated Wenling Hospital, Wenzhou Medical University, Taizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Pneumatic tube systems (PTS) accelerate the transport of samples in the laboratory but may lead to preanalytical hemolysis. Samples may rest before transport during busy times, but the effect on test accuracy is unclear. This study presents a novel single-tube PTS with a secondary deceleration device and LIS integration, evaluating its impact on routine biochemical parameters and examining the effects of prolonged sample resting times before PTS transport. Methods: In a prospective study of 34 outpatients, four blood samples per participant were collected in silica-clot activator tubes. Samples were randomly allocated to: immediate PTS transport (Group A), PTS after 15-min rest (B), PTS after 30-min rest (C), or manual delivery (Group D). All samples from each subject were centrifuged and analyzed simultaneously upon arrival. Twenty-two biochemical parameters were measured; results for PTS groups were compared to the manual control, with bias assessed against ±1/2 total allowable error (±1/2TEa). Results: The hemolysis index (HI) was negative for both PTS and HD groups. Lactate dehydrogenase (LDH) levels were significantly elevated in all PTS groups versus manual delivery ( Conclusion: The single-tube PTS is suitable for transporting blood specimens for biochemical analysis. To maintain the reliability of biochemical results from silica-clot activator tubes, laboratories should minimize pre-transport delays and include resting time as a critical variable in PTS validation protocols.

Indexed as

blood specimen collectionclinical chemistryhemolysislaboratoriespneumatic transportation system

Identifiers

PMID41743645
PMCPMC12929093

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