ArticleSage open pediatrics
Predicting Pediatric Sepsis Outcomes: A Comparison of 3 Sepsis Risk Scores in Bangladesh.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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18 authors.
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Abstract
Background/Objective: Pediatric sepsis remains a leading cause of child mortality worldwide. Early risk stratification using organ dysfunction scores may improve management. Bangladesh bears a high burden of pediatric infectious disease and sepsis, particularly in children under 5. This study compared the predictive performance of admission PELOD-2, pSOFA, and Phoenix Sepsis Scores for in-hospital mortality among pediatric sepsis patients. Methods: We conducted a secondary analysis of an observational study at a tertiary hospital in Dhaka, Bangladesh (February-December 2022). Of 100 enrolled children aged 2 months to 18 years with sepsis, 96 had sufficient data for score calculation. Results: Median age was 8 months (IQR 5-18), and in-hospital mortality was 23%. Admission PELOD-2 >3 and pSOFA >6 were associated with increased mortality. AUCs for mortality were 0.83 (pSOFA), 0.82 (PELOD-2), and 0.79 (Phoenix). Conclusions: All 3 scores showed good mortality discrimination. pSOFA and Phoenix may be more feasible in low-resource settings.
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